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|---|---|
| Accession Number: | Q9H2D1 |
| Protein Name: | hMFT aka MFT |
| Length: | 315 |
| Molecular Weight: | 35407.00 |
| Species: | Homo sapiens (Human) [9606] |
| Number of TMSs: | 6 |
| Location1 / Topology2 / Orientation3: | Mitochondrion inner membrane1 / Multi-pass membrane protein2 |
| Substrate | folic acid |
Cross database links:
| RefSeq: | NP_110407.2 |
|---|---|
| Entrez Gene ID: | 81034 |
| Pfam: | PF00153 |
| OMIM: |
610815 gene |
| KEGG: | hsa:81034 hsa:81034 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005743
C:mitochondrial inner membrane
GO:0005488
F:binding
GO:0008517
F:folic acid transporter activity
GO:0015884
P:folic acid transport
GO:0046655
P:folic acid metabolic process
GO:0006839
P:mitochondrial transport
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References (6)[1] “Retrovirally mediated complementation of the glyB phenotype. Cloning of a human gene encoding the carrier for entry of folates into mitochondria.” Titus S.A.et.al. 10978331 [2] “Complete sequencing and characterization of 21,243 full-length human cDNAs.” Ota T.et.al. 14702039 [3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [4] “Retrovirally mediated complementation of the glyB phenotype. Cloning of a human gene encoding the carrier for entry of folates into mitochondria.” Titus S.A.et.al. 10978331 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MTGQGQSASG SSAWSTVFRH VRYENLIAGV SGGVLSNLAL HPLDLVKIRF AVSDGLELRP 61: KYNGILHCLT TIWKLDGLRG LYQGVTPNIW GAGLSWGLYF FFYNAIKSYK TEGRAERLEA 121: TEYLVSAAEA GAMTLCITNP LWVTKTRLML QYDAVVNSPH RQYKGMFDTL VKIYKYEGVR 181: GLYKGFVPGL FGTSHGALQF MAYELLKLKY NQHINRLPEA QLSTVEYISV AALSKIFAVA 241: ATYPYQVVRA RLQDQHMFYS GVIDVITKTW RKEGVGGFYK GIAPNLIRVT PACCITFVVY 301: ENVSHFLLDL REKRK