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|---|---|
| Accession Number: | P16260 |
| Protein Name: | Graves disease carrier protein |
| Length: | 332 |
| Molecular Weight: | 36224.00 |
| Species: | Homo sapiens (Human) [9606] |
| Number of TMSs: | 6 |
| Location1 / Topology2 / Orientation3: | Mitochondrion inner membrane1 / Multi-pass membrane protein2 |
| Substrate | coenzyme A |
Cross database links:
| Entrez Gene ID: | 8034 |
|---|---|
| Pfam: | PF00153 |
| KEGG: | hsa:8034 hsa:8034 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005743
C:mitochondrial inner membrane
GO:0005488
F:binding
GO:0015300
F:solute:solute antiporter activity
GO:0009108
P:coenzyme biosynthetic process
GO:0015939
P:pantothenate metabolic process
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References (12)[1] “Sequence and chromosomal assignment of a novel cDNA identified by immunoscreening of a thyroid expression library: similarity to a family of mitochondrial solute carrier proteins.” Zarrilli R.et.al. 2575220 [2] “Sequence and pattern of expression of a bovine homologue of a human mitochondrial transport protein associated with Grave's disease.” Fiermonte G.et.al. 1457817 [3] “Complete sequencing and characterization of 21,243 full-length human cDNAs.” Ota T.et.al. 14702039 [4] “The DNA sequence and comparative analysis of human chromosome 10.” Deloukas P.et.al. 15164054 [5] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [6] “The yeast mitochondrial carrier Leu5p and its human homologue Graves' disease protein are required for accumulation of coenzyme A in the matrix.” Prohl C.et.al. 11158296 [7] “Sequence and chromosomal assignment of a novel cDNA identified by immunoscreening of a thyroid expression library: similarity to a family of mitochondrial solute carrier proteins.” Zarrilli R.et.al. 2575220 [8] “Sequence and pattern of expression of a bovine homologue of a human mitochondrial transport protein associated with Grave's disease.” Fiermonte G.et.al. 1457817 [9] “Complete sequencing and characterization of 21,243 full-length human cDNAs.” Ota T.et.al. 14702039 [10] “The DNA sequence and comparative analysis of human chromosome 10.” Deloukas P.et.al. 15164054 [11] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [12] “The yeast mitochondrial carrier Leu5p and its human homologue Graves' disease protein are required for accumulation of coenzyme A in the matrix.” Prohl C.et.al. 11158296
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MAAATAAAAL AAADPPPAMP QAAGAGGPTT RRDFYWLRSF LAGGIAGCCA KTTVAPLDRV 61: KVLLQAHNHH YKHLGVFSAL RAVPQKEGFL GLYKGNGAMM IRIFPYGAIQ FMAFEHYKTL 121: ITTKLGISGH VHRLMAGSMA GMTAVICTYP LDMVRVRLAF QVKGEHSYTG IIHAFKTIYA 181: KEGGFFGFYR GLMPTILGMA PYAGVSFFTF GTLKSVGLSH APTLLGRPSS DNPNVLVLKT 241: HVNLLCGGVA GAIAQTISYP FDVTRRRMQL GTVLPEFEKC LTMRDTMKYV YGHHGIRKGL 301: YRGLSLNYIR CIPSQAVAFT TYELMKQFFH LN