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Accession Number: | Q9H1K4 |
Protein Name: | Mitochondrial glutamate carrier 2 |
Length: | 315 |
Molecular Weight: | 33849.00 |
Species: | Homo sapiens (Human) [9606] |
Number of TMSs: | 6 |
Location1 / Topology2 / Orientation3: | Mitochondrion inner membrane1 / Multi-pass membrane protein2 |
Substrate | glutamate(2-) |
Cross database links:
Entrez Gene ID: | 83733 |
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Pfam: | PF00153 |
KEGG: | hsa:83733 hsa:83733 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005743
C:mitochondrial inner membrane
GO:0005488
F:binding
GO:0015293
F:symporter activity
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References (8)[1] “Identification of the mitochondrial glutamate transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution of two human isoforms.” Fiermonte G.et.al. 11897791 [2] “Analysis of the cat eye syndrome critical region in humans and the region of conserved synteny in mice: a search for candidate genes at or near the human chromosome 22 pericentromere.” Footz T.K.et.al. 11381032 [3] “A genome annotation-driven approach to cloning the human ORFeome.” Collins J.E.et.al. 15461802 [4] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [5] “Identification of the mitochondrial glutamate transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution of two human isoforms.” Fiermonte G.et.al. 11897791 [6] “Analysis of the cat eye syndrome critical region in humans and the region of conserved synteny in mice: a search for candidate genes at or near the human chromosome 22 pericentromere.” Footz T.K.et.al. 11381032 |
External Searches:
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Analyze:
Predict TMSs (Predict number of transmembrane segments) | ||||
FASTA formatted sequence |
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1: MTHQDLSITA KLINGGVAGL VGVTCVFPID LAKTRLQNQH GKAMYKGMID CLMKTARAEG 61: FFGMYRGAAV NLTLVTPEKA IKLAANDFFR RLLMEDGMQR NLKMEMLAGC GAGMCQVVVT 121: CPMEMLKIQL QDAGRLAVHH QGSASAPSTS RSYTTGSAST HRRPSATLIA WELLRTQGLA 181: GLYRGLGATL LRDIPFSIIY FPLFANLNNL GFNELAGKAS FAHSFVSGCV AGSIAAVAVT 241: PLDVLKTRIQ TLKKGLGEDM YSGITDCARK LWIQEGPSAF MKGAGCRALV IAPLFGIAQG 301: VYFIGIGERI LKCFD