2.A.29.18.5
Inner membrane mitochondrial magnesium exporter, Mme1 of 347 aas and 6 (- 8?) TMSs. Deletion of MME1 significantly increased steady-state mitochondrial Mg2+ concentrations, while overexpression decreased them. Measurements of Mg2+ exit from proteoliposomes reconstituted with purified Mme1 provided
definite evidence that Mme1 is an Mg2+ exporter (Cui et al. 2015).
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| Accession Number: | F2QTU3 |
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| Protein Name: | Putative transporter of the mitochondrial inner membrane |
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| Length: | 347 |
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| Molecular Weight: | 38060.00 |
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| Species: | Komagataella phaffii (strain ATCC 76273 / CBS 7435 / CECT 11047 / NRRL Y-11430 / Wegner 21-1) (Yeast) [981350] |
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| Number of TMSs: | 2 |
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| Substrate |
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1: MEKYNTASLP LGFENDHYIK PHTILQEEEG PSNESSPLWH CIVAGGIGGM VGDSTMHSLD
61: TVKTRQQGAP TVAVYKNMTS AYATIFRQEG FRRGLYGGYG AAMLGSFPST AVFFGTYESV
121: KRLMIGRWNC NETATHLVAG FLGDFFSSVF YVPSEVLKTR LQLQGRYNNP YFHSGYNYKS
181: TAHAITSIIK SEGWQTLFFG YKATLVRDLP FSALQFAFYE KFRSWALRVS SANHHDLSVL
241: WELATGAAAG GLAGTLTTPL DVIKTRIQTQ NAASTVSSSS SGKPIILSSP SILSSLLMVY
301: KHEGALGLFS GVGPRFIWTS VQSSIMLLLY QVSLRTLDDM LEGTALD