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|---|---|
| Accession Number: | Q9UBX3 |
| Protein Name: | Mitochondrial dicarboxylate carrier |
| Length: | 287 |
| Molecular Weight: | 31282.00 |
| Species: | Homo sapiens (Human) [9606] |
| Number of TMSs: | 3 |
| Location1 / Topology2 / Orientation3: | Mitochondrion inner membrane1 / Multi-pass membrane protein2 |
| Substrate | phosphate(3-), sulfate, thiosulfate(2-), malate(2-), succinate(2-) |
Cross database links:
| RefSeq: | NP_036272.2 |
|---|---|
| Entrez Gene ID: | 1468 |
| Pfam: | PF00153 |
| OMIM: |
606794 gene |
| KEGG: | hsa:1468 hsa:1468 hsa:1468 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005743
C:mitochondrial inner membrane
GO:0005310
F:dicarboxylic acid transmembrane transporter...
GO:0005515
F:protein binding
GO:0006835
P:dicarboxylic acid transport
GO:0006094
P:gluconeogenesis
GO:0006839
P:mitochondrial transport
GO:0055085
P:transmembrane transport
GO:0005634
C:nucleus
GO:0005310
F:dicarboxylic acid transmembrane transporter activity
GO:0006811
P:ion transport
GO:0070221
P:sulfide oxidation, using sulfide:quinone oxidoreductase
GO:0000098
P:sulfur amino acid catabolic process
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References (11)[1] “Organization and sequence of the gene for the human mitochondrial dicarboxylate carrier: evolution of the carrier family.” Fiermonte G.et.al. 10585886 [2] “Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.” Otsuki T.et.al. 16303743 [3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [4] “Organization and sequence of the gene for the human mitochondrial dicarboxylate carrier: evolution of the carrier family.” Fiermonte G.et.al. 10585886 [5] “Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.” Otsuki T.et.al. 16303743 [6] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [7] “Initial characterization of the human central proteome.” Burkard T.R.et.al. 21269460 [8] “Organization and sequence of the gene for the human mitochondrial dicarboxylate carrier: evolution of the carrier family.” Fiermonte G.et.al. 10585886 [9] “Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.” Otsuki T.et.al. 16303743 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MAAEARVSRW YFGGLASCGA ACCTHPLDLL KVHLQTQQEV KLRMTGMALR VVRTDGILAL 61: YSGLSASLCR QMTYSLTRFA IYETVRDRVA KGSQGPLPFH EKVLLGSVSG LAGGFVGTPA 121: DLVNVRMQND VKLPQGQRRN YAHALDGLYR VAREEGLRRL FSGATMASSR GALVTVGQLS 181: CYDQAKQLVL STGYLSDNIF THFVASFIAG GCATFLCQPL DVLKTRLMNS KGEYQGVFHC 241: AVETAKLGPL AFYKGLVPAG IRLIPHTVLT FVFLEQLRKN FGIKVPS