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|---|---|
| Accession Number: | Q6KCM7 |
| Protein Name: | Calcium-binding mitochondrial carrier protein SCaMC-2 |
| Length: | 469 |
| Molecular Weight: | 52663.00 |
| Species: | [9606] |
| Number of TMSs: | 4 |
| Location1 / Topology2 / Orientation3: | Mitochondrion inner membrane1 / Multi-pass membrane protein2 |
| Substrate | magnesium(2+), phosphate(3-), ATP |
Cross database links:
| RefSeq: | NP_001006642.1 NP_001006643.1 NP_001006644.1 NP_443133.2 XP_002346240.1 XP_002346241.1 |
|---|---|
| Entrez Gene ID: | 100292202 114789 |
| Pfam: | PF00153 |
| OMIM: |
608745 gene |
| KEGG: | hsa:100292202 hsa:114789 hsa:114789 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005743
C:mitochondrial inner membrane
GO:0005509
F:calcium ion binding
GO:0055085
P:transmembrane transport
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References (14)[1] “Identification of a novel human subfamily of mitochondrial carriers with calcium-binding domains.” del Arco A.et.al. 15054102 [2] “Identification of the mitochondrial ATP-Mg/Pi transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution.” Fiermonte G.et.al. 15123600 [3] “Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins.” Nagase T.et.al. 11572484 [4] “The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.” Clark H.F.et.al. 12975309 [5] “Complete sequencing and characterization of 21,243 full-length human cDNAs.” Ota T.et.al. 14702039 [6] “DNA sequence and analysis of human chromosome 9.” Humphray S.J.et.al. 15164053 [7] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [8] “Identification of a novel human subfamily of mitochondrial carriers with calcium-binding domains.” del Arco A.et.al. 15054102 [9] “Identification of the mitochondrial ATP-Mg/Pi transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution.” Fiermonte G.et.al. 15123600 [10] “Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins.” Nagase T.et.al. 11572484 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MLCLCLYVPV IGEAQTEFQY FESKGLPAEL KSIFKLSVFI PSQEFSTYRQ WKQKIVQAGD 61: KDLDGQLDFE EFVHYLQDHE KKLRLVFKSL DKKNDGRIDA QEIMQSLRDL GVKISEQQAE 121: KILKSMDKNG TMTIDWNEWR DYHLLHPVEN IPEIILYWKH STIFDVGENL TVPDEFTVEE 181: RQTGMWWRHL VAGGGAGAVS RTCTAPLDRL KVLMQVHASR SNNMGIVGGF TQMIREGGAR 241: SLWRGNGINV LKIAPESAIK FMAYEQIKRL VGSDQETLRI HERLVAGSLA GAIAQSSIYP 301: MEVLKTRMAL RKTGQYSGML DCARRILARE GVAAFYKGYV PNMLGIIPYA GIDLAVYETL 361: KNAWLQHYAV NSADPGVFVL LACGTMSSTC GQLASYPLAL VRTRMQAQAS IEGAPEVTMS 421: SLFKHILRTE GAFGLYRGLA PNFMKVIPAV SISYVVYENL KITLGVQSR