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Accession Number: | O95258 |
Protein Name: | Brain mitochondrial carrier protein-1 (BMCP-1) (Mitochondrial uncoupling protein 5) (UCP 5) (Solute carrier family 25, member 14) |
Length: | 325 |
Molecular Weight: | 36202.00 |
Species: | Homo sapiens (Human) [9606] |
Number of TMSs: | 7 |
Location1 / Topology2 / Orientation3: | Mitochondrion inner membrane1 / Multi-pass membrane protein2 |
Substrate | chloride, hydron, dicarboxylic acid dianion, phosphate(3-), sulfate, thiosulfate(2-), sulfurous acid, glutamate(2-), citramalate(2-), aspartate(2-), tricarboxylic acid trianion, malonate ester, malate(2-) |
Cross database links:
RefSeq: | NP_003942.1 NP_073721.1 |
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Entrez Gene ID: | 9016 |
Pfam: | PF00153 |
OMIM: |
300242 gene |
KEGG: | hsa:9016 hsa:9016 |
Gene Ontology
GO:0005887
C:integral to plasma membrane
GO:0005743
C:mitochondrial inner membrane
GO:0005488
F:binding
GO:0009060
P:aerobic respiration
GO:0006839
P:mitochondrial transport
GO:0055085
P:transmembrane transport
GO:0005739
C:mitochondrion
GO:0006810
P:transport
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References (10)[1] “BMCP1, a novel mitochondrial carrier with high expression in the central nervous system of humans and rodents, and respiration uncoupling activity in recombinant yeast.” Sanchis D.et.al. 9852133 [2] “Characterization of novel UCP5/BMCP1 isoforms and differential regulation of UCP4 and UCP5 expression through dietary or temperature manipulation.” Yu X.X.et.al. 10928996 [3] “The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.” Clark H.F.et.al. 12975309 [4] “The DNA sequence of the human X chromosome.” Ross M.T.et.al. 15772651 [5] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [6] “BMCP1, a novel mitochondrial carrier with high expression in the central nervous system of humans and rodents, and respiration uncoupling activity in recombinant yeast.” Sanchis D.et.al. 9852133 [7] “Characterization of novel UCP5/BMCP1 isoforms and differential regulation of UCP4 and UCP5 expression through dietary or temperature manipulation.” Yu X.X.et.al. 10928996 [8] “The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.” Clark H.F.et.al. 12975309 |
External Searches:
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Analyze:
Predict TMSs (Predict number of transmembrane segments) | ||||
FASTA formatted sequence |
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1: MGIFPGIILI FLRVKFATAA VIVSGHQKST TVSHEMSGLN WKPFVYGGLA SIVAEFGTFP 61: VDLTKTRLQV QGQSIDARFK EIKYRGMFHA LFRICKEEGV LALYSGIAPA LLRQASYGTI 121: KIGIYQSLKR LFVERLEDET LLINMICGVV SGVISSTIAN PTDVLKIRMQ AQGSLFQGSM 181: IGSFIDIYQQ EGTRGLWRGV VPTAQRAAIV VGVELPVYDI TKKHLILSGM MGDTILTHFV 241: SSFTCGLAGA LASNPVDVVR TRMMNQRAIV GHVDLYKGTV DGILKMWKHE GFFALYKGFW 301: PNWLRLGPWN IIFFITYEQL KRLQI