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|---|---|
| Accession Number: | O95847 |
| Protein Name: | Mitochondrial uncoupling protein 4 |
| Length: | 323 |
| Molecular Weight: | 36064.00 |
| Species: | Homo sapiens (Human) [9606] |
| Number of TMSs: | 5 |
| Location1 / Topology2 / Orientation3: | Mitochondrion inner membrane1 / Multi-pass membrane protein2 |
| Substrate | chloride, hydron |
Cross database links:
| Entrez Gene ID: | 9481 |
|---|---|
| Pfam: | PF00153 |
| KEGG: | hsa:9481 hsa:9481 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005743
C:mitochondrial inner membrane
GO:0006091
P:generation of precursor metabolites and energy
GO:0006810
P:transport
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References (4)[1] “UCP4, a novel brain-specific mitochondrial protein that reduces membrane potential in mammalian cells.” Mao W.et.al. 10025957 [2] “The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.” Clark H.F.et.al. 12975309 [3] “UCP4, a novel brain-specific mitochondrial protein that reduces membrane potential in mammalian cells.” Mao W.et.al. 10025957 [4] “The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.” Clark H.F.et.al. 12975309
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MSVPEEEERL LPLTQRWPRA SKFLLSGCAA TVAELATFPL DLTKTRLQMQ GEAALARLGD 61: GARESAPYRG MVRTALGIIE EEGFLKLWQG VTPAIYRHVV YSGGRMVTYE HLREVVFGKS 121: EDEHYPLWKS VIGGMMAGVI GQFLANPTDL VKVQMQMEGK RKLEGKPLRF RGVHHAFAKI 181: LAEGGIRGLW AGWVPNIQRA ALVNMGDLTT YDTVKHYLVL NTPLEDNIMT HGLSSLCSGL 241: VASILGTPAD VIKSRIMNQP RDKQGRGLLY KSSTDCLIQA VQGEGFMSLY KGFLPSWLRM 301: TPWSMVFWLT YEKIREMSGV SPF