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2.A.29.3.3
The uncoupling protein, UCP1 or PUMP1 (functions to relieve oxidative stress, and to allow efficient photosynthesis (Sweetlove et al., 2006).  In some plants, it is activated in response to cold stress and may control reactive oxygen species (Valente et al. 2012). In addition to protons, it transports a variety of anions including aspartate, glutamate, cysteine sulfinate, cysteate, dicarboxylates (malate, oxaloacetate, oxaloglutarate), phosphate, sulfate and thiosulfate. It functions preferentially as an anion exchanger, but more slowly as an anion uniporter. A primary function may be aspartate/glutamate antiport, thereby contributing to the export of reducing equivalents from the mitochondria in photorespiration. (Monné et al. 2018).

Accession Number:O65623
Protein Name:Plant uncoupling mitochondrial protein aka PUMP aka UCP1
Length:306
Molecular Weight:32704.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:3
Location1 / Topology2 / Orientation3: Mitochondrion inner membrane1 / Multi-pass membrane protein2
Substrate dicarboxylic acid dianion, phosphate(3-), sulfate, thiosulfate(2-), glutamate(2-), aspartate(2-), oxaloacetate(2-), malate(2-)

Cross database links:

Pfam: PF00153   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005739 C:mitochondrion
GO:0005488 F:binding
GO:0006839 P:mitochondrial transport
GO:0055085 P:transmembrane transport

References (1)

[1] “AtPUMP: an Arabidopsis gene encoding a plant uncoupling mitochondrial protein.”  Maia I.G.et.al.   9662458

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MVAAGKSDLS LPKTFACSAF AACVGEVCTI PLDTAKVRLQ LQKSALAGDV TLPKYRGLLG 
61:	TVGTIAREEG LRSLWKGVVP GLHRQCLFGG LRIGMYEPVK NLYVGKDFVG DVPLSKKILA 
121:	GLTTGALGIM VANPTDLVKV RLQAEGKLAA GAPRRYSGAL NAYSTIVRQE GVRALWTVLG 
181:	PNVARNAIIN AAELASYDQV KETILKIPGF TDNVVTHILS GLGAGFFAVC IGSPVDVVKS 
241:	RMMGDSGAYK GTIDCFVKTL KSDGPMAFYK GFIPNFGRLG SWNVIMFLTL EQAKKYVREL 
301:	DASKRN