2.A.29.3.8
Dicarboxylate transporter, UCP2 or PUMP2 of 305 aas and 6 TMSs. It transports aspartate, glutamate, non-amino acid dicarboxylates (malate, oxaloacetate, oxaloglutarate), cysteine suflinate, cysteate, and inorganic phosphate. It is a fast antiporter and a slow uniporter (Monné et al. 2018).
|
| Accession Number: | Q9ZWG1 |
|---|
| Protein Name: | Mitochondrial uncoupling protein 2 |
|---|
| Length: | 305 |
|---|
| Molecular Weight: | 33442.00 |
|---|
| Species: | Arabidopsis thaliana (Mouse-ear cress) [3702] |
|---|
| Number of TMSs: | 5 |
|---|
| Location1 / Topology2 / Orientation3: |
Mitochondrion inner membrane1 / Multi-pass membrane protein2 |
|---|
| Substrate |
dicarboxylic acid dianion, phosphate(3-), sulfate, thiosulfate(2-), glutamate(2-), aspartate(2-), oxaloacetate(2-), malate(2-) |
|---|
1: MADFKPRIEI SFLETFICSA FAACFAELCT IPLDTAKVRL QLQRKIPTGD GENLPKYRGS
61: IGTLATIARE EGISGLWKGV IAGLHRQCIY GGLRIGLYEP VKTLLVGSDF IGDIPLYQKI
121: LAALLTGAIA IIVANPTDLV KVRLQSEGKL PAGVPRRYAG AVDAYFTIVK LEGVSALWTG
181: LGPNIARNAI VNAAELASYD QIKETIMKIP FFRDSVLTHL LAGLAAGFFA VCIGSPIDVV
241: KSRMMGDSTY RNTVDCFIKT MKTEGIMAFY KGFLPNFTRL GTWNAIMFLT LEQVKKVFLR
301: EVLYD