2.A.29.31.1
Sequence-divergent mitochondrial carrier of 394 aas and 6 TMSs, MCP14. The T. brucei MCP14 appears to be involved in energy metabolism but it also mediates drug action and is required for cell growth and viability (de Macêdo et al. 2015). TbMCP14 belongs to a trypanosomatid-specific clade of the mitochondrial carrier family.
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| Accession Number: | K4DWH6 |
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| Protein Name: | Mitochondrial carrier protein, putative |
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| Length: | 394 |
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| Molecular Weight: | 43157.00 |
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| Species: | Trypanosoma cruzi [5693] |
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| Number of TMSs: | 6 |
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| Substrate |
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1: MMTTCENVRG VLQNCGDAAP LPSESLSTNA VNRSLSDLHT PTWFVLLGLS SGLRTLLLHP
61: LNLAISRKRM MAESRPPPVM QILSQAYRGE AKTSPLNPTK GVRAIYRGFG VALIGNLFGE
121: VAYLHTLELV REELESKPSA LQGASSSQGL DFNASSHAAA AGGLAGGLIS LLITTPMSVV
181: CNRQLTAGYG MASGYTYCSA WATGREVSGL YRKTNESFLR RGKYALRGFY AGLLPGIAAL
241: PEYAVWWALY SKTKVVLYTL FEPTLSRWER ERDANDSIRP FWRQNWLLSP TDNPALNAAA
301: GMLASSITTV VFNPLDVIHT RLQVLPLERH GKAKGVPFAR VYNLVDSLIR KEGWRGLFKG
361: ASANVSASVL DGVFFSLFFE LTKLGSDREF LRQF