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2.A.29.5.1 MRS3 iron (Fe²⁺) import carrier in the inner mitochondrial membrane; essential for erythroid iron utilization) (Mühlenhoff et al., 2003). Uptake is dependent on the pH gradient (Froschauer et al. 2009).
Accession Number:	P10566
Protein Name:	MRS3 aka YJL133W aka J0675
Length:	314
Molecular Weight:	34502.00
Species:	Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:	6
Location¹ / Topology² / Orientation³:	Mitochondrion inner membrane¹ / Multi-pass membrane protein²
Substrate	iron(2+)

DIP:	DIP-8202N
RefSeq:	NP_012402.1
Entrez Gene ID:	853308
Pfam:	PF00153
KEGG:	sce:YJL133W
Gene Ontology GO:0016021 C:integral to membrane GO:0005743 C:mitochondrial inner membrane GO:0005381 F:iron ion transmembrane transporter activity GO:0005515 F:protein binding GO:0048250 P:mitochondrial iron ion transport GO:0006397 P:mRNA processing GO:0008380 P:RNA splicing GO:0055085 P:transmembrane transport
References (5) [1] “Nuclear suppression of a mitochondrial RNA splice defect: nucleotide sequence and disruption of the MRS3 gene.” Schmidt C.et.al. 2448588 [2] “MRS3 and MRS4, two suppressors of mtRNA splicing defects in yeast, are new members of the mitochondrial carrier family.” Wiesenberger G.et.al. 1703236 [3] “Sequence analysis of a 40.7 kb segment from the left arm of yeast chromosome X reveals 14 known genes and 13 new open reading frames including homologues of genes clustered on the right arm of chromosome XI.” Katsoulou C.et.al. 8813765 [4] “Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.” Galibert F.et.al. 8641269 [5] “Global analysis of protein expression in yeast.” Ghaemmaghami S.et.al. 14562106

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FASTA formatted sequence

1:	MVENSSSNNS TRPIPAIPMD LPDYEALPTH APLYHQLIAG AFAGIMEHSV MFPIDALKTR 
61:	IQSANAKSLS AKNMLSQISH ISTSEGTLAL WKGVQSVILG AGPAHAVYFG TYEFCKKNLI 
121:	DSSDTQTHHP FKTAISGACA TTASDALMNP FDTIKQRIQL NTSASVWQTT KQIYQSEGLA 
181:	AFYYSYPTTL VMNIPFAAFN FVIYESSTKF LNPSNEYNPL IHCLCGSISG STCAAITTPL 
241:	DCIKTVLQIR GSQTVSLEIM RKADTFSKAA SAIYQVYGWK GFWRGWKPRI VANMPATAIS 
301:	WTAYECAKHF LMTY

2.A.29.5.1
MRS3 iron (Fe²⁺) import carrier in the inner mitochondrial membrane; essential for erythroid iron utilization) (Mühlenhoff et al., 2003). Uptake is dependent on the pH gradient (Froschauer et al. 2009).

Cross database links:

Gene Ontology

References (5)

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2.A.29.5.1MRS3 iron (Fe2+) import carrier in the inner mitochondrial membrane; essential for erythroid iron utilization) (Mühlenhoff et al., 2003). Uptake is dependent on the pH gradient (Froschauer et al. 2009).

Cross database links:

Gene Ontology

References (5)

External Searches:

Analyze:

2.A.29.5.1
MRS3 iron (Fe²⁺) import carrier in the inner mitochondrial membrane; essential for erythroid iron utilization) (Mühlenhoff et al., 2003). Uptake is dependent on the pH gradient (Froschauer et al. 2009).