TCDB » SEARCH

« See all members of the family

2.A.29.8.5 The carnitine:acylcarnitine exchange translocase, CACL. CACL is similar in tissue distribution to that of CACT (TC# 2.A.29.8.3); both are expressed at a higher level in tissues using fatty acids as fuels, except the brain, where only CACL is expressed (Sekoguchi et al., 2003)
Accession Number:	Q8BL03
Protein Name:	Mitochondrial carnitine/acylcarnitine carrier protein CACL
Length:	306
Molecular Weight:	32672.00
Species:	Mus musculus (Mouse) [10090]
Number of TMSs:	4
Location¹ / Topology² / Orientation³:	Mitochondrion inner membrane¹ / Multi-pass membrane protein²
Substrate	S-adenosyl-L-methionine, carnitinium

RefSeq:	NP_851845.1
Entrez Gene ID:	214663
Pfam:	PF00153
KEGG:	mmu:214663 mmu:214663
Gene Ontology GO:0016021 C:integral to membrane GO:0005743 C:mitochondrial inner membrane GO:0015227 F:acyl carnitine transporter activity GO:0005488 F:binding GO:0006844 P:acyl carnitine transport GO:0055085 P:transmembrane transport
References (6) [1] “A novel mitochondrial carnitine-acylcarnitine translocase induced by partial hepatectomy and fasting.” Sekoguchi E.et.al. 12882971 [2] “The transcriptional landscape of the mammalian genome.” Carninci P.et.al. 16141072 [3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [4] “A novel mitochondrial carnitine-acylcarnitine translocase induced by partial hepatectomy and fasting.” Sekoguchi E.et.al. 12882971 [5] “The transcriptional landscape of the mammalian genome.” Carninci P.et.al. 16141072 [6] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MALDFLAGCA GGVAGVIVGH PFDIVKVRLQ VQSTEKPQYR GTLHCFQSII KQESVLGLYK 
61:	GLGSPLMGLT FINALVFGVQ GNTLRALGQD SPLNQFLAGA AAGAIQCVIC CPMELAKTRL 
121:	QLQAVGPART YKGSLDCLVQ IYRHEGLRGI NRGMVSTLLR ETPSFGVYFL TYDVMTRAMG 
181:	CEPGDRLLVP KLLLAGGTSG ITSWLSTYPM DVVKSRLQAD GLQGTPRYRG IVDCMRQSYQ 
241:	AEGWQVFTRG LASTLLRAFP VNAATFATVT VVLTYTRGEE AQVDSEAALG TSPTPAGSAL 
301:	AQPSSL

2.A.29.8.5
The carnitine:acylcarnitine exchange translocase, CACL. CACL is similar in tissue distribution to that of CACT (TC# 2.A.29.8.3); both are expressed at a higher level in tissues using fatty acids as fuels, except the brain, where only CACL is expressed (Sekoguchi et al., 2003)

Cross database links:

Gene Ontology

References (6)

External Searches:

Analyze:

2.A.29.8.5The carnitine:acylcarnitine exchange translocase, CACL. CACL is similar in tissue distribution to that of CACT (TC# 2.A.29.8.3); both are expressed at a higher level in tissues using fatty acids as fuels, except the brain, where only CACL is expressed (Sekoguchi et al., 2003)

Cross database links:

Gene Ontology

References (6)

External Searches:

Analyze:

2.A.29.8.5
The carnitine:acylcarnitine exchange translocase, CACL. CACL is similar in tissue distribution to that of CACT (TC# 2.A.29.8.3); both are expressed at a higher level in tissues using fatty acids as fuels, except the brain, where only CACL is expressed (Sekoguchi et al., 2003)