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2.A.32.1.1
Silicon transporter of 548 aas and 10 probable TMSs in a 2 + 3 + 2 + 3 TMS arrangement. It has a conserved aa motif, CMLD. Hydropathy profiles suggest that CMLD occupies a position between two TMSs. These two TMSs are candidates for a role of the channel through which transport of silicic acid occurs (Shcherbakova et al. 2006).

Accession Number:Q39510
Protein Name:Sit1
Length:548
Molecular Weight:60572.00
Species:Cylindrotheca fusiformis (Marine diatom) [2853]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Apical cell membrane1 / Multi-pass membrane protein2
Substrate silicon atom, silicate(4-)

Cross database links:

Pfam: PF03842   

References (1)

[1] “A gene family of silicon transporters.”  Hildebrand M.et.al.   9034185

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MVSVIDGIKQ FYSMALVIFS VVIVTALMFT DNTKLAKDAH PVAALVIMWL GILWMSMVEG 
61:	GQCSMVGLPP IDRDLYKESH PITYKICSLG HKGNNLDRYL MGRQFMVIFI NFTINLCGAP 
121:	LEGAEVLGLP EILTDIFLGS GIAMVLTVVT IGQLTAQVNA SHCMLDYINT HFMTFTLYVT 
181:	LVIEATGVMH SCYLIRDMFY HAAGKPVETN EPPRSAVQNL FHWGRVVFSL GVLCFALAVT 
241:	IEALFNGKTT MWEFIPNGVA IVLFILLMSV VGLLEGMQIA FFAVAKIPKA ERGDHPFARK 
301:	TCELLFKGKG RNLPGFMVGR QMTVTLCFFI IARVTTLDIE VGVDDNIFGV SDGIQEFFNL 
361:	GFLGAIITTI LASIAWQLVA SAFPIAFLSN PIVYIVLRIV LLIEATGICA GAWFLGMIHK 
421:	KVAGFQLDEV YVGTAEERAA GMKPDHSIHA GREFTMGTNV LNDRKNWEET IANLSAKETF 
481:	SVRRERMLKN IRELRAMAEE ASSPEEKATF ETAPTMETKA LNKLNEEQEK EATLQKDSSD 
541:	TENEADLA