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2.A.40.6.1 L-ascorbate:Na⁺ symporter, SVCT1. (L-ascorbate:Na⁺= 1:2; Mackenzie et al., 2008). Iron regulates SVCT1 in human intestinal Caco-2 cells (Scheers and Sandberg, 2011).
Accession Number:	Q9WTW7
Protein Name:	SLC23A1 aka SVCT1
Length:	604
Molecular Weight:	65263.00
Species:	Rattus norvegicus (Rat) [10116]
Number of TMSs:	11
Location¹ / Topology² / Orientation³:	Membrane¹ / Multi-pass membrane protein²
Substrate	sodium(1+), L-ascorbic acid

RefSeq:	NP_059011.1
Entrez Gene ID:	50621
Pfam:	PF00860
KEGG:	rno:50621
Gene Ontology GO:0009925 C:basal plasma membrane GO:0005903 C:brush border GO:0005737 C:cytoplasm GO:0005887 C:integral to plasma membrane GO:0008520 F:L-ascorbate:sodium symporter activity GO:0015229 F:L-ascorbic acid transporter activity GO:0015882 P:L-ascorbic acid transport GO:0006814 P:sodium ion transport
References (2) [1] “A family of mammalian Na+-dependent L-ascorbic acid transporters.” Tsukaguchi H.et.al. 10331392 [2] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MKAQEDPGSS KQHECPDSAG TSTRDQQAPL PAEPKFDMLY KIEDVPPWYL CILLGFQHYL 
61:	TCFSGTIAVP FLLAEALCVG RDQHMISQLI GTIFTCVGIT TLIQTTVGIR LPLFQASAFA 
121:	FLVPAKAILA LERWKCPPEE EIYGNWSMPL NTSHIWHPRI REVQGAIMVS SVVEVVIGLL 
181:	GLPGALLSYI GPLTVTPTVS LIGLSVFQAA GDRAGSHWGI SACSILLIVL FSQYLRNLTF 
241:	LLPVYRWGKG LTLFRIQIFK MFPIVLAIMT VWLLCYVLTL TDVLPADPTV YGFQARTDAR 
301:	GDIMAISPWI RIPYPCQWGL PTVTVAAVLG MFSATLAGII ESIGDYYACA RLAGAPPPPV 
361:	HAINRGIFTE GVCCIIAGLL GTGNGSTSSS PNIGVLGITK VGSRRVVQYG AGIMLILGAI 
421:	GKFTALFASL PDPILGGMFC TLFGMITAVG LSNLQFVDMN SSRNLFVLGF SMFFGLTLPN 
481:	YLDSNPGAIN TGVPEVDQIL TVLLTTEMFV GGCLAFILDN TVPGSPEERG LIQWKAGAHA 
541:	NSETLASLKS YDFPFGMGMV KRTTFFRYIP ICPVFRGFSK TENQPAVLED APDNTETGSV 
601:	CTKV

2.A.40.6.1
L-ascorbate:Na⁺ symporter, SVCT1. (L-ascorbate:Na⁺= 1:2; Mackenzie et al., 2008). Iron regulates SVCT1 in human intestinal Caco-2 cells (Scheers and Sandberg, 2011).

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

2.A.40.6.1L-ascorbate:Na+ symporter, SVCT1. (L-ascorbate:Na+= 1:2; Mackenzie et al., 2008). Iron regulates SVCT1 in human intestinal Caco-2 cells (Scheers and Sandberg, 2011).

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

2.A.40.6.1
L-ascorbate:Na⁺ symporter, SVCT1. (L-ascorbate:Na⁺= 1:2; Mackenzie et al., 2008). Iron regulates SVCT1 in human intestinal Caco-2 cells (Scheers and Sandberg, 2011).