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2.A.42.1.2 High affinity (3 μM tryptophan permease, Mtr. Also transports indole. It functions to scavenge trace amounts of tryptophan in the medium for protein synthesis when concentrations are very low (Gu et al. 2013).
Accession Number:	P0AAD2
Protein Name:	Tryptophan-specific transport protein Mtr aka B3161
Length:	414
Molecular Weight:	44333.00
Species:	Escherichia coli [83333]
Number of TMSs:	11
Location¹ / Topology² / Orientation³:	Cell inner membrane¹ / Multi-pass membrane protein²
Substrate	tryptophan, 1H-indole

RefSeq:	AP_003706.1 NP_417630.1
Entrez Gene ID:	947675
Pfam:	PF03222
BioCyc:	EcoCyc:MTR-MONOMER ECOL168927:B3161-MONOMER
KEGG:	ecj:JW3130 eco:b3161
Gene Ontology GO:0016021 C:integral to membrane GO:0005886 C:plasma membrane GO:0006865 P:amino acid transport
References (7) [1] “Cloning, nucleotide sequence, and characterization of mtr, the structural gene for a tryptophan-specific permease of Escherichia coli K-12.” Heatwole V.M.et.al. 1987112 [2] “Regulation of expression of the Escherichia coli K-12 mtr gene by TyrR protein and Trp repressor.” Sarsero J.P.et.al. 2061290 [3] “The complete genome sequence of Escherichia coli K-12.” Blattner F.R.et.al. 9278503 [4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.” Hayashi K.et.al. 16738553 [5] “The tryptophan-specific permease gene, mtr, is differentially regulated by the tryptophan and tyrosine repressors in Escherichia coli K-12.” Heatwole V.M.et.al. 1904443 [6] “Membrane topology analysis of Escherichia coli K-12 Mtr permease by alkaline phosphatase and beta-galactosidase fusions.” Sarsero J.P.et.al. 7814318 [7] “Global topology analysis of the Escherichia coli inner membrane proteome.” Daley D.O.et.al. 15919996

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FASTA formatted sequence

1:	MATLTTTQTS PSLLGGVVII GGTIIGAGMF SLPVVMSGAW FFWSMAALIF TWFCMLHSGL 
61:	MILEANLNYR IGSSFDTITK DLLGKGWNVV NGISIAFVLY ILTYAYISAS GSILHHTFAE 
121:	MSLNVPARAA GFGFALLVAF VVWLSTKAVS RMTAIVLGAK VITFFLTFGS LLGHVQPATL 
181:	FNVAESNASY APYLLMTLPF CLASFGYHGN VPSLMKYYGK DPKTIVKCLV YGTLMALALY 
241:	TIWLLATMGN IPRPEFIGIA EKGGNIDVLV QALSGVLNSR SLDLLLVVFS NFAVASSFLG 
301:	VTLGLFDYLA DLFGFDDSAV GRLKTALLTF APPVVGGLLF PNGFLYAIGY AGLAATIWAA 
361:	IVPALLARAS RKRFGSPKFR VWGGKPMIAL ILVFGVGNAL VHILSSFNLL PVYQ

2.A.42.1.2
High affinity (3 μM tryptophan permease, Mtr. Also transports indole. It functions to scavenge trace amounts of tryptophan in the medium for protein synthesis when concentrations are very low (Gu et al. 2013).

Cross database links:

Gene Ontology

References (7)

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2.A.42.1.2High affinity (3 μM tryptophan permease, Mtr. Also transports indole. It functions to scavenge trace amounts of tryptophan in the medium for protein synthesis when concentrations are very low (Gu et al. 2013).

Cross database links:

Gene Ontology

References (7)

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2.A.42.1.2
High affinity (3 μM tryptophan permease, Mtr. Also transports indole. It functions to scavenge trace amounts of tryptophan in the medium for protein synthesis when concentrations are very low (Gu et al. 2013).