2.A.42.2.4
Inner membrane inducible, anaerobic, cysteine uptake transport protein, CyuP (DlsT; YhaO) of 443 aas and 11 TMSs (Loddeke et al. 2017). It is in a bicistronic operon with CyuA, an iron-sulfur-containing cysteine desulfidase, and this operon is regulated by the CyuR protein and induced maximally under anaerobic conditions. L-cysteine, D-cysteine, and a few other sulfur-containing compounds can serve as inducers. This system has been characterized both in E. coli and in S. enterica (Loddeke et al. 2017).
|
| Accession Number: | P42628 |
|---|
| Protein Name: | Inner membrane transport protein YhaO |
|---|
| Length: | 443 |
|---|
| Molecular Weight: | 48315.00 |
|---|
| Species: | Escherichia coli (strain K12) [83333] |
|---|
| Number of TMSs: | 11 |
|---|
| Location1 / Topology2 / Orientation3: |
Cell inner membrane1 / Multi-pass membrane protein2 |
|---|
| Substrate |
|
|---|
| Entrez Gene ID: |
947628
|
|---|
| KEGG: |
eco:b3110
|
|---|
|
|
[1] “The complete genome sequence of Escherichia coli K-12.” Blattner F.R. et.al. 9278503
[2] “Escherichia coli K-12: a cooperatively developed annotation snapshot -- 2005.” Riley M. et.al. 16397293
[3] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.” Hayashi K. et.al. 16738553
[4] “Global topology analysis of the Escherichia coli inner membrane proteome.” Daley D.O. et.al. 15919996
|
1: MEIASNKGVI ADASTPAGRA GMSESEWREA IKFDSTDTGW VIMSIGMAIG AGIVFLPVQV
61: GLMGLWVFLL SSVIGYPAMY LFQRLFINTL AESPECKDYP SVISGYLGKN WGILLGALYF
121: VMLVIWMFVY STAITNDSAS YLHTFGVTEG LLSDSPFYGL VLICILVAIS SRGEKLLFKI
181: STGMVLTKLL VVAALGVSMV GMWHLYNVGS LPPLGLLVKN AIITLPFTLT SILFIQTLSP
241: MVISYRSREK SIEVARHKAL RAMNIAFGIL FVTVFFYAVS FTLAMGHDEA VKAYEQNISA
301: LAIAAQFISG DGAAWVKVVS VILNIFAVMT AFFGVYLGFR EATQGIVMNI LRRKMPAEKI
361: NENLVQRGIM IFAILLAWSA IVLNAPVLSF TSICSPIFGM VGCLIPAWLV YKVPALHKYK
421: GMSLYLIIVT GLLLCVSPFL AFS