TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
2.A.45.1.1









Arsenical resistance efflux pump (exports As(III) and Sb(III) probably as polymers of the hydroxides using an H+ antiport mechanism) (Meng et al., 2004)
Bacteria
Firmicutes
ArsB of Staphylococcus aureus
2.A.45.1.2









Arsenic transporter, ArsB, of 422 aas and 11 TMSs.

Bacteria
Proteobacteria
ArsB of Campylobacter coli
2.A.45.2.1









P-protein; possible tyrosine transporter (also called "melanocyte-specific transporter", "oculocutaneous albinism-related protein (Oca2)" and "pink-eyed dilution gene product").  It has been reported to exhibit chloride-selective anion channel activity and to be required for melanin production, possibly by controling melanosome pH (Bellono et al. 2014). Its function has been reviewed (Wiriyasermkul et al. 2020).

Eukaryota
Metazoa
P-protein of Homo sapiens
2.A.45.2.2









Uncharacterized transporter Mb2703
Bacteria
Actinobacteria
Mb2703 of Mycobacterium bovis
2.A.45.2.3









Putative ion transporter in magnetosome membranes of magentotactic bacteria, MamN of 437 aas and 10 TMSs (Murat et al. 2010). Uebe and Schüler 2016 considered that MamN might be a proton exporter that releases H+ from the magentosome matrix to the cytosol. 

Bacteria
Proteobacteria
MamN of Magnetospirillum gryphiswaldense
2.A.45.2.4









The plasma membrane silicon (silicate) efflux pump, Low Silicon 2, Lsi2 (localized to the proximal side of the cell, whereas the silicon uptake system, Lsi1 (TC# 1.A.8.12.2) is localized to the distal side of the same cells) (Ma et al., 2007a, b).
Eukaryota
Viridiplantae
Lsi2 of Oryza sativa
(Q10SY9)
2.A.45.2.5









Inner membrane protein YbiR
Bacteria
Proteobacteria
YBIR of Escherichia coli K-12
2.A.45.2.6









Putative plasma membrane low silicon efflux pump, Lsi2, of 393 aas and 12 TMSs.

Bacteria
Actinobacteria
Lsi2 of Bifidobacterium asteroides
2.A.45.3.1









Putative transporter
Bacteria
Firmicutes
Putative transporter of Bacillus cereus (gi 30021968)
2.A.45.3.2









Uncharaterized protein of 570 aas and 14 TMSs in a 7 + 7 arrangement.

Bacteria
Actinobacteria
UP of Nocardioides sp.