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| Accession Number: | P37020 |
| Protein Name: | Voltage-gated chloride channel aka Gef1 |
| Length: | 779 |
| Molecular Weight: | 87683.00 |
| Species: | Saccharomyces cerevisiae (Baker's yeast) [4932] |
| Number of TMSs: | 11 |
| Location1 / Topology2 / Orientation3: | Membrane1 / Multi-pass membrane protein2 |
| Substrate | chloride |
Cross database links:
| DIP: | DIP-3949N |
|---|---|
| RefSeq: | NP_012574.1 |
| Entrez Gene ID: | 853497 |
| Pfam: | PF00571 PF00654 |
| KEGG: | sce:YJR040W |
Gene Ontology
GO:0034707
C:chloride channel complex
GO:0005783
C:endoplasmic reticulum
GO:0005768
C:endosome
GO:0000324
C:fungal-type vacuole
GO:0005797
C:Golgi medial cisterna
GO:0005886
C:plasma membrane
GO:0005515
F:protein binding
GO:0005247
F:voltage-gated chloride channel activity
GO:0006878
P:cellular copper ion homeostasis
GO:0006879
P:cellular iron ion homeostasis
GO:0006821
P:chloride transport
GO:0055085
P:transmembrane transport
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References (7)[1] “The GEF1 gene of Saccharomyces cerevisiae encodes an integral membrane protein; mutations in which have effects on respiration and iron-limited growth.” Greene J.R.et.al. 7505388 [2] “A voltage-gated chloride channel in the yeast Saccharomyces cerevisiae.” Huang M.-E.et.al. 7932715 [3] “Analysis of a 42.5 kb DNA sequence of chromosome X reveals three tRNA genes and 14 new open reading frames including a gene most probably belonging to the family of ubiquitin-protein ligases.” Huang M.-E.et.al. 7668047 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MPTTYVPINQ PIRDGEDVID TNRFTNIPET QNFDQFVTID KIAEENRPLS VDSDREFLNS 61: KYRHYREVIW DRAKTFITLS STAIVIGCIA GFLQVFTETL VNWKTGHCQR NWLLNKSFCC 121: NGVVNEVTST SNLLLKRQEF ECEAQGLWIA WKGHVSPFII FMLLSVLFAL ISTLLVKYVA 181: PMATGSGISE IKVWVSGFEY NKEFLGLLTL VIKSVALPLA ISSGLSVGKE GPSVHYATCC 241: GYLLTKWLLR DTLTYSTQYE YLTAASGAGV AVAFGAPIGG VLFGLEEIAS ANRFNSSTLW 301: KSYYVALVAI TTLKYIDPFR NGRVILFNVT YDRDWKVQEI PIFIALGIFG GLYGKYISKW 361: NINFIHFRKM YLSSWPVQEV LFLATLTALI SYFNEFLKLD MTESMGILFH ECVKNDNTST 421: FSHRLCQLDE NTHAFEFLKI FTSLCFATVI RALLVVVSYG ARVPAGIFVP SMAVGATFGR 481: AVSLLVERFI SGPSVIIPGA YAFLGAAATL SGITNLTLTV VVIMFELTGA FMYIIPLMIV 541: VAITRIILST SGISGGIADQ MIMVNGFPYL EDEQDEEEEE TLEKYTAEQL MSSKLITINE 601: TIYLSELESL LYDSASEYSV HGFPITKDED KFEKEKRCIG YVLKRHLASK IMMQSVNSTK 661: AQTTLVYFNK SNEELGHREN CIGFKDIMNE SPISVKKAVP VTLLFRMFKE LGCKTIIVEE 721: SGILKGLVTA KDILRFKRIK YREVHGAKFT YNEALDRRCW SVIHFIIKRF TTNRNGNVI