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| Accession Number: | Q874K8 |
| Protein Name: | CLC-A |
| Length: | 864 |
| Molecular Weight: | 96076.00 |
| Species: | Cryptococcus neoformans var. grubii (Filobasidiella neoformans var. grubii) [178876] |
| Number of TMSs: | 11 |
| Location1 / Topology2 / Orientation3: | Secreted1 |
| Substrate | chloride |
Cross database links:
| Pfam: | PF00571 PF00654 |
|---|---|
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005247
F:voltage-gated chloride channel activity
GO:0006821
P:chloride transport
GO:0055085
P:transmembrane transport
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References (1)[1] “A CLC-type chloride channel gene is required for laccase activity and virulence in Cryptococcus neoformans.” Zhu X.et.al. 14622414
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MPRQQSEDEH RICGQAFRSP RSPQGNPLER NSKLEDEEEL DLIRRYEDFS TVDWIQDSLH 61: ERTFQNKAPR SRVIAQLDRS DGAIGYLWRL IRRTLEEGEA YVVISLVGVI IGVSAALISI 121: ITTWLSDIKL GHCTTGWWLS RKFCCLEVSD ELEACAEWKN WGGVEPFRWI AYVLFAAAFS 181: FSAAYLVKNF APYAAGSGIS EIKCILGGFI INGFLSVETF FIKGLTLPLA IASGLAVGKE 241: GPSVHVACSV GNVVAKWFNR YERSHLKMRE IVTASSAAGV AVAFGSPIGG VLFSIEEMNQ 301: TYSNRTMWRS FVCALVATFT LASMDPFRTG KLVIFNVSYD RDWHYFEIPA YVLIGIFGGL 361: YGAFVIKFNV QMAAFRRKHL SGHGIFEAVA LASITAIIGY LNGFLRIDMT EMLSVLFREC 421: EGGGDYNGLC QASSQWRMVN SLLLATIIRT VFIIVSYGCK VPAGIFVPSM AVGATFGRMI 481: GILVKAMYNS YPSAPWFAAC APDAPCITPG TYAFLGAAAA MGGITRLTVT VVVIMFELTG 541: ALTYILPTMI VLLVTKAVSD QFGGGGISDH MIKFNGYPFL EKEDKEDPTD HAFIEPIANV 601: MKKDLIILEA TGVPLNHVVD IVQHTNYQGF PVVKSHEDQT IVGFVRKNEL RIALEKTRRV 661: RNLSFNATCT FQCIRAIPED AHELLERPDI LIPNREGRMT ANTGTENRED DGGEISHVDF 721: GQYVDDIPLT VAPKMPLEIV MQLFRRMGPR VILVSDQGRL TGLVTVKDVL RHELSEAHHR 781: SRSTHTPITP SHPAYAQSNG WDTEWTVDDE RGHGLEIVLE EGLEWTRSKA TWAYGAALER 841: WRDIRGQDRR AATFDYELDE GIQG