2.A.49.2.9
The CIC carrier (stoichiometry H+:Cl- = 2:1). 3D structure known to 3.5 Å resolution (PDB# 3ORG; Feng et al., 2010).
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| Accession Number: | M1UVK6 |
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| Protein Name: | Probable CLC-type chloride channel |
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| Length: | 715 |
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| Molecular Weight: | 78082.00 |
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| Species: | Cyanidioschyzon merolae strain 10D [280699] |
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| Number of TMSs: | 9 |
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| Substrate |
chloride, hydron |
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1: MSSKITGTLE VDYGLLDSMG NLARHPTPVG TRASESSQQI SLEETESGLR LAPYDTGFDA
61: NERSYGSVSP RDAYRCWNAL GSCTPRGSLM YLLRLVCFLT LLGVTAALFI FAVDLAVHGL
121: EELRMKISRL AGRFAGYILY VVSGVALCLL STFWCAVLST EAEGSGLPQM KSILSGFYDK
181: MRSALELRVL FAKALGLICA IGGGLPVGWE GPNVHIACII AHQFYRLGVF KELCTDRALR
241: LQTLAAACAV GLASSFGAPL GGVLYSIETI ASFYLVQAFW KGVLSALSGA IVYELLYTTP
301: LVEAFEGTNF DASDVSRTQT LLYAILGALM GVLGALFIRC VRSIYELRMR HYPGTNRYFL
361: VGVVALFASA LQYPFRLFAL DPRATINDLF KAVPLYQTDH FGWTELILMP IIKFILVALS
421: IGLPLPAGVF VPSFLIGAGF GRLYGELMRV VFGNAIVPGS YAVVGAAAFT AGVTRALSCA
481: VIIFEVTGQI RHLVPVLISV LLAVIVGNAF NRSLYETLVL MKHLPYMPIL RRDRSPEMTA
541: REIMHPIEGE PHLFPDSEPQ HIKGILEKFP NRLVFPVIDA NGYLLGAISR KEIVDRLQHV
601: LEDVPEPIAG HRTLVLLDAA DLSENIEGLV DETPSGEHSS KGKRTATVLE PTSSLVVPCD
661: VSPIVVTSYS LVRQLHFLFV MLMPSMIYVT ERGKLVGIVE REDVAYGYRE PEQTS