TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.49.3.2
Mitochondrial inner membrane anion channel (IMAC). Fatty acids induce chloride permeation in rat liver mitochondria probably by activation of the inner membrane anion channel (IMAC) (Schönfeld et al. 2004).

Accession Number:Q9XF71
Protein Name:ClC-Nt2
Length:786
Molecular Weight:86614.00
Species:Nicotiana tabacum (Common tobacco) [4097]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Golgi apparatus membrane1 / Multi-pass membrane protein2
Substrate anions

Cross database links:

Pfam: PF00571    PF00654   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005247 F:voltage-gated chloride channel activity
GO:0006821 P:chloride transport
GO:0055085 P:transmembrane transport

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MEEPTRLVEE ATINNMDGQQ NEEERDPESN SLHQPLLKRN RTLSSSPFAL VGAKVSHIES 
61:	LDYEINENDL FKHDWRRRSR VQVLQYVFLK WTLAFLVGLL TGVTATLINL AIENMAGYKL 
121:	RAVVNYIEDR RYLMGFAYFA GANFVLTLIA ALLCVCFAPT AAGPGIPEIK AYLNGVDTPN 
181:	MYGATTLFVK IIGSIAAVSA SLDLGKEGPL VHIGACFASL LGQGGPDNYR LRWRWLRYFN 
241:	NDRDRRDLIT CGSSSGVCAA FRSPVGGVLF ALEEVATWWR SALLWRTFFS TAVVVVILRA 
301:	FIEYCKSGNC GLFGRGGLIM FDVSGVSVSY HVVDIIPVVV IGIIGGLLGS LYNHVLHKIL 
361:	RLYNLINEKG KLHKVLLALS VSLFTSICMY GLPFLAKCKP CDPSLPGSCP GTGGTGNFKQ 
421:	FNCPDGYYND LATLLLTTND DAVRNIFSIN TPGEFQVMSL ISYFVLYCIL GLITFGIAVP 
481:	SGLFLPIILM GSAYGRLLAI AMGSYTKIDP GLYAVLGAAS LMAGSMRMTV SLCVIFLELT 
541:	NNLLLLPITM LVLLIAKSVG DCFNLSIYEI ILELKGLPFL DANPEPWMRN ITAGELADVK 
601:	PPVVTLCGVE KVGRIVEALK NTTYNGFPVV DEGVVPPVGL PVGATELHGL VLRTHLLLVL 
661:	KKKWFLHERR RTEEWEVREK FTWIDLAERG GKIEDVLVTK DEMEMYVDLH PLTNTTPYTV 
721:	VESLSVAKAM VLFRQVGLRH MLIVPKYQAA GVSPVVGILT RQDLRAHNIL SVFPHLEKSK 
781:	SGKKGN