2.A.49.6.5
Uncharacterized membrane protein of 481 aas and 10 - 13 TMSs. This protein was probably incorrectly assigned the function as the membrane constituent of an ABC Zn2+ uptake transporter (Mandal et al. 2019). However, this is unlikely; it is probably a Cl- transporter in agreement with its assignment to TC family 2.A.49.
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| Accession Number: | Q5SKP5 |
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| Protein Name: | Putative transport integral membrane protein (Chloride channel) |
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| Length: | 481 |
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| Molecular Weight: | 48863.00 |
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| Species: | Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) [300852] |
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| Number of TMSs: | 10 |
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| Substrate |
inorganic anion, chloride |
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1: MELLGEEGRR LLRLGLLPGL LGGGLAVAFR LLLDLLLLVP PLALPLAGGA VGLFSAWLYR
61: RLPDLRGGGA DRVLLAYHLG QGRLPPRLGP LKALLTALTL GLGGSGGQEG PLLYAGGALA
121: QALRPRNPAE ARAVLLAGGA AAIAALFHTP LGAAFFAAEV LYRGSALEGR LLGYLAVAAI
181: SGYGLQSLLF GTHPLLPVQG LEAPPLWFAL ALAPLAALGA FALARGLAWS RARLQGPAAL
241: PLALAASGTL ALLFPPARGT SYEGLAALLQ GEGPNPFLFL LAKALAVLLS AGSGASVGLF
301: GPSVVLGGAL GAALGALFGI GGPGPILLGL VALVSAAART PFAAVVQMVE ITGSYALLVP
361: GLLVAFGAFA LNRETLFPLQ PPGPEASPAH AEDLLRGLAQ LPPGRPLLLG DLGAVLLEVR
421: EGHPWAGKPL KDTALPPGVL VGLVFRQAHL LAPRGQDRLE PGDRVLLLGP KEEVARFAAR
481: S