2.A.5.1.14 Low affinity zinc-regulated zinc uptake transporter, Zrt2 of 422 aas and 7 TMSs. Active in zinc-replete cells and is time-,
temperature- and concentration-dependent. It prefers zinc over other
metals as its substrate (Zhao and Eide 1996).
|
Accession Number: | Q12436 |
Protein Name: | Zinc-regulated transporter 2 |
Length: | 422 |
Molecular Weight: | 46363.00 |
Species: | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292] |
Number of TMSs: | 7 |
Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
Substrate |
zinc(2+) |
---|
1: MVDLIARDDS VDTCQASNGY NGHAGLRILA VFIILISSGL GVYFPILSSR YSFIRLPNWC
61: FFIAKFFGSG VIVATAFVHL LQPAAEALGD ECLGGTFAEY PWAFGICLMS LFLLFFTEII
121: THYFVAKTLG HDHGDHGEVT SIDVDAPSSG FVIRNMDSDP VSFNNEAAYS IHNDKTPYTT
181: RNEEIVATPI KEKEPGSNVT NYDLEPGKTE SLANELVPTS SHATNLASVP GKDHYSHEND
241: HQDVSQLATR IEEEDKEQYL NQILAVFILE FGIIFHSVFV GLSLSVAGEE FETLFIVLTF
301: HQMFEGLGLG TRVAETNWPE SKKYMPWLMG LAFTLTSPIA VAVGIGVRHS WIPGSRRALI
361: ANGVFDSISS GILIYTGLVE LMAHEFLYSN QFKGPDGLKK MLSAYLIMCC GAALMALLGK
421: WA