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2.A.5.1.6
The Zn2+/Cd2+ transporter, ZNT1 (Nishida et al., 2011).  The histidine-rich loop between TMSs 3 and 4 binds Cu2+ > Zn2+ > Ni2+ (Potocki et al. 2014). Expression of particular transmembrane transporters (e.g., members of the ZIP (ZNT1) and NRAMP (NRAMP4) families) leads to metal tolerance and accumulation in plants (Fasani et al. 2021).

Accession Number:Q9M7J1
Protein Name:Zn and Cd transporter ZNT1
Length:378
Molecular Weight:39550.00
Species:Thlaspi caerulescens (Alpine penny-cress) [107243]
Number of TMSs:8
Substrate

Cross database links:

Pfam: PF02535   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005385 F:zinc ion transmembrane transporter activity

References (1)

[1] “The molecular physiology of heavy metal transport in the Zn/Cd hyperaccumulator Thlaspi caerulescens.”  Pence N.S.et.al.   10781104

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MASSPTKILC DAGESDLCRD DAAAFLLKFV AIASILLAGA AGVAIPLIGK NRRFLQTEGN 
61:	LFVAAKAFAA GVILATGFVH MLAGGTEALT NPCLPDYPWS KFPFPGFFAM VAALITLLVD 
121:	FMGTQYYESK QQRNEVAGGG EAAVVEETSS VLPVVVERGN DSKAFGEEDG GGMHIVGIRA 
181:	HAAHHNHSHS NAHGTFDGHA HGQSHGHVHV HGSHDVENGA RHVVVSQILE LGIVSHSIII 
241:	GLSLGVSQSP CTIRPLIAAL SFHQFFEGFA LGGCISQAQF KNKSAIIMAC FFALTAPIGI 
301:	GIGTAVASSF NSHSPGALVT EGILDSLSAG ILTYMALVDL IAADFLSKRM SCNVRLQVVS 
361:	YVMLFLGAGL MSALAIWA