2.A.5.4.20 Zinc/Iron transporter, Zip13 (gene: Zip99c) of 355 aas and 8 TMSs. A conserved motif in TMS4 is DNXXH instead of the usual HNXXD; only the former motif, not the latter, allows iron transport (Zhao and Zhou 2019).
|
Accession Number: | Q9VAF0 |
Protein Name: | Zinc transporter ZIP13 homolog |
Length: | 355 |
Molecular Weight: | 38870.00 |
Species: | Drosophila melanogaster (Fruit fly) [7227] |
Number of TMSs: | 8 |
Location1 / Topology2 / Orientation3: |
Basolateral cell membrane1 / Multi-pass membrane protein2 |
Substrate |
iron(2+), zinc(2+) |
---|
1: MTTNSSFFDE HIAMIYSNLM DQYMPEYFKS FEYTPWVFSL LGSVVIGLSG IFPLIIIPTE
61: EKMAKEGYKD PADSKLLRVL LSFAVGGLLG DVFLHLLPEA WEGDNQDPSS HPSLRSGLWV
121: LSGILIFTIV EKIFSGYASA DEENPQPKCV EIANCLLRRH GGQLPEGETS ESCGGACDIE
181: DVGKVCFLRE QEQKSKERKE QPKKVAGYLN LLANSIDNFT HGLAVAGSFL VSFRHGILAT
241: FAILLHEIPH EVGDFAILLR SGFSRWDAAR AQLLTAGAGL LGALVAIGGS GVTSAMEART
301: SWIMPFTAGG FLHIALVTVL PDLLKEEERK ESIKQLLALV FGIALMAVMT MLFEH