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|---|---|
| Accession Number: | Q92504 |
| Protein Name: | Ke4 |
| Length: | 469 |
| Molecular Weight: | 50118.00 |
| Species: | Homo sapiens (Human) [9606] |
| Number of TMSs: | 7 |
| Location1 / Topology2 / Orientation3: | Membrane1 / Multi-pass membrane protein2 |
| Substrate | zinc(2+) |
Cross database links:
| RefSeq: | NP_001070984.1 NP_008910.2 |
|---|---|
| Entrez Gene ID: | 7922 |
| Pfam: | PF02535 |
| OMIM: |
601416 gene |
| KEGG: | hsa:7922 hsa:7922 |
Gene Ontology
GO:0005789
C:endoplasmic reticulum membrane
GO:0016021
C:integral to membrane
GO:0005624
C:membrane fraction
GO:0005515
F:protein binding
GO:0005385
F:zinc ion transmembrane transporter activity
GO:0055085
P:transmembrane transport
GO:0006829
P:zinc ion transport
GO:0046873
F:metal ion transmembrane transporter activity
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References (16)[1] “cDNA cloning of the human homologues of the mouse Ke4 and Ke6 genes at the centromeric end of the human MHC region.” Ando A.et.al. 8812499 [2] “The DNA sequence and analysis of human chromosome 6.” Mungall A.J.et.al. 14574404 [3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [4] “Structure-function analysis of LIV-1, the breast cancer-associated protein that belongs to a new subfamily of zinc transporters.” Taylor K.M.et.al. 12839489 [5] “Global phosphoproteome of HT-29 human colon adenocarcinoma cells.” Kim J.-E.et.al. 16083285 [6] “Phosphoproteome of resting human platelets.” Zahedi R.P.et.al. 18088087 [7] “Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.” Daub H.et.al. 18691976 [8] “Large-scale proteomics analysis of the human kinome.” Oppermann F.S.et.al. 19369195 [9] “cDNA cloning of the human homologues of the mouse Ke4 and Ke6 genes at the centromeric end of the human MHC region.” Ando A.et.al. 8812499 [10] “The DNA sequence and analysis of human chromosome 6.” Mungall A.J.et.al. 14574404 [11] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [12] “Structure-function analysis of LIV-1, the breast cancer-associated protein that belongs to a new subfamily of zinc transporters.” Taylor K.M.et.al. 12839489 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MARGLGAPHW VAVGLLTWAT LGLLVAGLGG HDDLHDDLQE DFHGHSHRHS HEDFHHGHSH 61: AHGHGHTHES IWHGHTHDHD HGHSHEDLHH GHSHGYSHES LYHRGHGHDH EHSHGGYGES 121: GAPGIKQDLD AVTLWAYALG ATVLISAAPF FVLFLIPVES NSPRHRSLLQ ILLSFASGGL 181: LGDAFLHLIP HALEPHSHHT LEQPGHGHSH SGQGPILSVG LWVLSGIVAF LVVEKFVRHV 241: KGGHGHSHGH GHAHSHTRGS HGHGRQERST KEKQSSEEEE KETRGVQKRR GGSTVPKDGP 301: VRPQNAEEEK RGLDLRVSGY LNLAADLAHN FTDGLAIGAS FRGGRGLGIL TTMTVLLHEV 361: PHEVGDFAIL VQSGCSKKQA MRLQLLTAVG ALAGTACALL TEGGAVGSEI AGGAGPGWVL 421: PFTAGGFIYV ATVSVLPELL REASPLQSLL EVLGLLGGVI MMVLIAHLE