TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
2.A.51.1.1









Chromate-resistance efflux pump
Bacteria
Proteobacteria
ChrA of Alcaligenes eutrophus
2.A.51.1.2









Chromate-sensitivity anion uptake permease
Bacteria
Cyanobacteria
SrpC of Synechococcus sp. PCC7942
2.A.51.1.3









Chromate-resistance efflux pump, ChrA of 416 aas and 11 or 12 TMSs. The chrA gene of Pseudomonas aeruginosa plasmid pUM505 encodes ChrA, which confers resistance to chromate by the energy-dependent efflux of chromate ions (Aguilera et al. 2004). Chromate-sensitive mutants were mostly point mutations affected amino acids clustered in the N-terminal half of ChrA, altering either cytoplasmic regions or transmembrane segments, and replaced residues moderately to highly conserved in ChrA homologs. PhoA and LacZ translational fusions were used to confirm the membrane topology at the N-terminal half of the ChrA protein (Aguilera et al. 2004).

Bacteria
Proteobacteria
ChrA of Pseudomonas aeruginosa plasmid pUM505
2.A.51.1.4









Chromate efflux transporter, ChrA (Aguilar-Barajas et al., 2008)
Bacteria
Proteobacteria
ChrA of Shewanella sp. strain ANA-3 (A0L3E7)
2.A.51.1.5









Chromate efflux protein Chr3N/Chr3C, or YwrB/YwrA (Díaz-Magaña et al., 2009).  Each protein has 5 TMSs, but they have antiparallel orientation in the membrane: Chr3N has the C-terminus in the cytoplasm while Chr3C has the C-terminus facing the extracellular medium (Martínez-Valencia et al. 2012).

Bacteria
Firmicutes
YwrB/YwrA or Chr3N/Chr3C of Bacillus subtilis
Chr3N (O05216)
Chr3C (O05215)
2.A.51.1.6









Putative two component chromate porter.  The two proteins each have 5 TMSs and are of 195 and 187 aas in length.

Bacteria
Spirochaetes
Two component transporter of Treponema denticola
2.A.51.1.7









Chromate resistance protein, ChrA, of 389 aas and 11 TMSs.

Bacteria
Proteobacteria
ChrA of E. coli
2.A.51.1.8









Chromate efflux transporter, ChrA, of 420 aas and 11 TMSs.

Archaea
Euryarchaeota
ChrA of Euryarchaeota archaeon TMED141 (marine metagenome)
2.A.51.1.9









Chromate sensitivity protein, a chromate uptake protein, Chr-1, of 560 aas and 9 - 11 TMSs. N. crassa CHR-1 takes up chromate in a sulfate-independent fashon (Flores-Alvarez et al. 2012).

Eukaryota
Fungi
Chr-1 of Neurospora crassa
2.A.51.1.10









Uncharacterized protein of 984 aas and 13 TMSs, 1 N-terminal and 12 C-terminal.

Eukaryota
Oomycota
UP of Phytophthora fragariae
2.A.51.1.11









Uncharacterized protein of 544 aas and 11 TMSs in a 4 + 7 TMS arrangement.

Eukaryota
Evosea
UP of Cavenderia fasciculata
2.A.51.1.12









Chromate transporter of 513 aas and 10 - 12 TMSs (Hori et al. 2014).

Eukaryota
Viridiplantae
Chromate transporter of Klebsormidium nitens