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|---|---|
| Accession Number: | Q8TB61 |
| Protein Name: | Adenosine 3'-phospho 5'-phosphosulfate transporter 1 aka SLC35B2 aka PAPST1 |
| Length: | 432 |
| Molecular Weight: | 47515.00 |
| Species: | Homo sapiens (Human) [9606] |
| Number of TMSs: | 9 |
| Location1 / Topology2 / Orientation3: | Golgi apparatus membrane1 / Multi-pass membrane protein2 |
| Substrate | |
Cross database links:
| RefSeq: | NP_835361.1 |
|---|---|
| Entrez Gene ID: | 347734 |
| Pfam: | PF08449 |
| OMIM: |
610788 gene |
| KEGG: | hsa:347734 hsa:347734 |
Gene Ontology
GO:0000139
C:Golgi membrane
GO:0016021
C:integral to membrane
GO:0046964
F:3'-phosphoadenosine 5'-phosphosulfate trans...
GO:0004871
F:signal transducer activity
GO:0046963
P:3'-phosphoadenosine 5'-phosphosulfate trans...
GO:0043123
P:positive regulation of I-kappaB kinase/NF-k...
GO:0055085
P:transmembrane transport
GO:0046964
F:3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity
GO:0043123
P:positive regulation of I-kappaB kinase/NF-kappaB cascade
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References (22)[1] “Molecular cloning and identification of 3'-phosphoadenosine 5'-phosphosulfate transporter.” Kamiyama S.et.al. 12716889 [2] “Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.” Matsuda A.et.al. 12761501 [3] “Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.” Otsuki T.et.al. 16303743 [4] “The DNA sequence and analysis of human chromosome 6.” Mungall A.J.et.al. 14574404 [5] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [6] “Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.” Olsen J.V.et.al. 17081983 [7] “Evaluation of the low-specificity protease elastase for large-scale phosphoproteome analysis.” Wang B.et.al. 19007248 [8] “Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.” Daub H.et.al. 18691976 [9] “A quantitative atlas of mitotic phosphorylation.” Dephoure N.et.al. 18669648 [10] “Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.” Gauci S.et.al. 19413330 [11] “Large-scale proteomics analysis of the human kinome.” Oppermann F.S.et.al. 19369195 [12] “Molecular cloning and identification of 3'-phosphoadenosine 5'-phosphosulfate transporter.” Kamiyama S.et.al. 12716889 [13] “Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.” Matsuda A.et.al. 12761501 [14] “Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.” Otsuki T.et.al. 16303743 [15] “The DNA sequence and analysis of human chromosome 6.” Mungall A.J.et.al. 14574404 [16] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [17] “Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.” Olsen J.V.et.al. 17081983 [18] “Evaluation of the low-specificity protease elastase for large-scale phosphoproteome analysis.” Wang B.et.al. 19007248 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MDARWWAVVV LAAFPSLGAG GETPEAPPES WTQLWFFRFV VNAAGYASFM VPGYLLVQYF 61: RRKNYLETGR GLCFPLVKAC VFGNEPKASD EVPLAPRTEA AETTPMWQAL KLLFCATGLQ 121: VSYLTWGVLQ ERVMTRSYGA TATSPGERFT DSQFLVLMNR VLALIVAGLS CVLCKQPRHG 181: APMYRYSFAS LSNVLSSWCQ YEALKFVSFP TQVLAKASKV IPVMLMGKLV SRRSYEHWEY 241: LTATLISIGV SMFLLSSGPE PRSSPATTLS GLILLAGYIA FDSFTSNWQD ALFAYKMSSV 301: QMMFGVNFFS CLFTVGSLLE QGALLEGTRF MGRHSEFAAH ALLLSICSAC GQLFIFYTIG 361: QFGAAVFTII MTLRQAFAIL LSCLLYGHTV TVVGGLGVAV VFAALLLRVY ARGRLKQRGK 421: KAVPVESPVQ KV