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2.A.7.12.1 CMP-sialic acid:CMP antiporter. Amino acid residues important for CMP-sialic acid recognition have been identified (Takeshima-Futagami et al., 2012). Residues essential for activity have been identified (Chan et al. 2010).
Accession Number:	Q61420
Protein Name:	CMST aka SLC35A1
Length:	336
Molecular Weight:	36409.00
Species:	Mus musculus (Mouse) [10090]
Number of TMSs:	10
Location¹ / Topology² / Orientation³:	Golgi apparatus membrane¹ / Multi-pass membrane protein²
Substrate	cytidine 5'-monophosphate, CMP-N-acetyl-beta-neuraminic acid

Structure:
RefSeq:	NP_036025.2
Entrez Gene ID:	24060
Pfam:	PF04142
KEGG:	mmu:24060
Gene Ontology GO:0000139 C:Golgi membrane GO:0016021 C:integral to membrane GO:0005338 F:nucleotide-sugar transmembrane transporter ... GO:0005351 F:sugar:hydrogen symporter activity GO:0015780 P:nucleotide-sugar transport
References (2) [1] “Expression cloning of the Golgi CMP-sialic acid transporter.” Eckhardt M.et.al. 8755516 [2] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334
6OH2 6OH3 6OH4

UniProt (Universal Protein Resource)
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FASTA formatted sequence

1:	MAPARENVSL FFKLYCLAVM TLVAAAYTVA LRYTRTTAEE LYFSTTAVCI TEVIKLLISV 
61:	GLLAKETGSL GRFKASLSEN VLGSPKELAK LSVPSLVYAV QNNMAFLALS NLDAAVYQVT 
121:	YQLKIPCTAL CTVLMLNRTL SKLQWISVFM LCGGVTLVQW KPAQASKVVV AQNPLLGFGA 
181:	IAIAVLCSGF AGVYFEKVLK SSDTSLWVRN IQMYLSGIVV TLAGTYLSDG AEIQEKGFFY 
241:	GYTYYVWFVI FLASVGGLYT SVVVKYTDNI MKGFSAAAAI VLSTIASVLL FGLQITLSFA 
301:	LGALLVCVSI YLYGLPRQDT TSIQQEATSK ERIIGV

2.A.7.12.1
CMP-sialic acid:CMP antiporter. Amino acid residues important for CMP-sialic acid recognition have been identified (Takeshima-Futagami et al., 2012). Residues essential for activity have been identified (Chan et al. 2010).

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

2.A.7.12.1CMP-sialic acid:CMP antiporter. Amino acid residues important for CMP-sialic acid recognition have been identified (Takeshima-Futagami et al., 2012). Residues essential for activity have been identified (Chan et al. 2010).

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

2.A.7.12.1
CMP-sialic acid:CMP antiporter. Amino acid residues important for CMP-sialic acid recognition have been identified (Takeshima-Futagami et al., 2012). Residues essential for activity have been identified (Chan et al. 2010).