| |
|---|---|
| Accession Number: | P40107 |
| Protein Name: | GOG5 aka VRG4 aka VAN2 aka VIG4 aka MCD3 aka YGL225W |
| Length: | 337 |
| Molecular Weight: | 37019.00 |
| Species: | Saccharomyces cerevisiae (Baker's yeast) [4932] |
| Number of TMSs: | 11 |
| Location1 / Topology2 / Orientation3: | Golgi apparatus membrane1 / Multi-pass membrane protein2 |
| Substrate | GDP-D-mannose |
Cross database links:
| DIP: | DIP-5108N |
|---|---|
| RefSeq: | NP_011290.1 |
| Entrez Gene ID: | 852647 |
| Pfam: | PF08449 |
| KEGG: | sce:YGL225W |
Gene Ontology
GO:0030659
C:cytoplasmic vesicle membrane
GO:0005789
C:endoplasmic reticulum membrane
GO:0000139
C:Golgi membrane
GO:0016021
C:integral to membrane
GO:0005739
C:mitochondrion
GO:0005338
F:nucleotide-sugar transmembrane transporter ...
GO:0005515
F:protein binding
GO:0030259
P:lipid glycosylation
GO:0015780
P:nucleotide-sugar transport
GO:0006487
P:protein amino acid N-linked glycosylation
GO:0055085
P:transmembrane transport
| |
References (18)[1] “The yeast VRG4 gene is required for normal Golgi functions and defines a new family of related genes.” Poster J.B.et.al. 8632002 [2] “Sodium orthovanadate-resistant mutants of Saccharomyces cerevisiae show defects in Golgi-mediated protein glycosylation, sporulation and detergent resistance.” Kanik-Ennulat C.et.al. 7672592 [3] “Sequence analysis of 203 kilobases from Saccharomyces cerevisiae chromosome VII.” Rieger M.et.al. 9290212 [4] “The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.” Tettelin H.et.al. 9169869 [5] “Vanadate-resistant mutants of Saccharomyces cerevisiae show alterations in protein phosphorylation and growth control.” Kanik-Ennulat C.et.al. 2137555 [6] “Vanadate-resistant yeast mutants are defective in protein glycosylation.” Ballou L.et.al. 2014241 [7] “Yeast glycosylation mutants are sensitive to aminoglycosides.” Dean N.et.al. 7877969 [8] “Identification of genes controlling growth polarity in the budding yeast Saccharomyces cerevisiae: a possible role of N-glycosylation and involvement of the exocyst complex.” Mondesert G.et.al. 9335583 [9] “Isolation of new nonconditional Saccharomyces cerevisiae mutants defective in asparagine-linked glycosylation.” Manas P.et.al. 9184829 [10] “The VRG4 gene is required for GDP-mannose transport into the lumen of the Golgi in the yeast, Saccharomyces cerevisiae.” Dean N.et.al. 9395539 [11] “Molecular characterization of Vig4/Vrg4 GDP-mannose transporter of the yeast Saccharomyces cerevisiae.” Abe M.et.al. 10570930 [12] “Identification of a conserved motif in the yeast golgi GDP-mannose transporter required for binding to nucleotide sugar.” Gao X.-D.et.al. 11067855 [13] “Progression of the stacked Golgi compartments in the yeast Saccharomyces cerevisiae by overproduction of GDP-mannose transporter.” Hashimoto H.et.al. 12478588 [14] “Global analysis of protein localization in budding yeast.” Huh W.-K.et.al. 14562095 | |
| Structure: | |
External Searches:
|
Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
|
|||
1: MSELKTGHAG HNPWASVANS GPISILSYCG SSILMTVTNK FVVNLKDFNM NFVMLFVQSL 61: VCTITLIILR ILGYAKFRSL NKTDAKNWFP ISFLLVLMIY TSSKALQYLA VPIYTIFKNL 121: TIILIAYGEV LFFGGSVTSM ELSSFLLMVL SSVVATWGDQ QAVAAKAASL AEGAAGAVAS 181: FNPGYFWMFT NCITSALFVL IMRKRIKLTN FKDFDTMFYN NVLALPILLL FSFCVEDWSS 241: VNLTNNFSND SLTAMIISGV ASVGISYCSG WCVRVTSSTT YSMVGALNKL PIALSGLIFF 301: DAPRNFLSIL SIFIGFLSGI IYAVAKQKKQ QAQPLRK