2.A.7.13.6 Golgi GDP-mannose transporter of 397 aas and 10 TMSs, Gmt1. Necessary for capsular biosynthesis, protein gycosylation and virulence (Wang et al. 2014).
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Accession Number: | P0CS02 |
Protein Name: | GDP-mannose transporter 1 |
Length: | 397 |
Molecular Weight: | 42883.00 |
Species: | Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) [214684] |
Number of TMSs: | 10 |
Location1 / Topology2 / Orientation3: |
Golgi apparatus membrane1 / Multi-pass membrane protein2 |
Substrate |
GDP-D-mannose |
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1: MSKPFVPTPN ISRPATPSSL DYGKDEASST LLRDMGERGD RERKDREERD KKEAMPSGQD
61: QVLPILSYCA ASIMMTVVNK YVVSGANFTM TFLLLAIQSS VCVLAVTTVK KLGFISFRDF
121: DKNDAKAWWP ISTLLVAVIY TGSKALQFLS IPVYTIFKNL TIILIAYGEV FMFNGAVSGL
181: TLCSFALMVG SSIIAAWSDI TSVWNKEPEL DPITGLEITV GPVSTIGGLN AGYIWMALNC
241: FVSAAYVLFM RKRIKVTGFK DWDSMYYNNL LSIPILVVFS LVIEDWGSES LALNFPASNR
301: VLLLSAMAFS GAAAVFISYS TAWCVRITGS TTYSMVGALN KLPVAASGIL FFGDPANFGN
361: ISAIAVGGVA GVVYAVAKTN QAKVEKARQA RAAGGRP