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Accession Number: | Q9NTN3 |
Protein Name: | Slc35D1 |
Length: | 355 |
Molecular Weight: | 39240.00 |
Species: | Homo sapiens (Human) [9606] |
Number of TMSs: | 10 |
Location1 / Topology2 / Orientation3: | Endoplasmic reticulum membrane1 / Multi-pass membrane protein2 |
Substrate | UDP-alpha-D-glucuronic acid, UDP-N-acetyl-alpha-D-galactosamine 4-sulfate |
Cross database links:
RefSeq: | NP_055954.1 |
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Entrez Gene ID: | 23169 |
Pfam: | PF03151 |
OMIM: |
269250 phenotype 610804 gene |
KEGG: | hsa:23169 hsa:23169 |
Gene Ontology
GO:0030176
C:integral to endoplasmic reticulum membrane
GO:0005461
F:UDP-glucuronic acid transmembrane transport...
GO:0005463
F:UDP-N-acetylgalactosamine transmembrane tra...
GO:0030206
P:chondroitin sulfate biosynthetic process
GO:0006065
P:UDP-glucuronate biosynthetic process
GO:0015789
P:UDP-N-acetylgalactosamine transport
GO:0005461
F:UDP-glucuronic acid transmembrane transporter activity
GO:0005463
F:UDP-N-acetylgalactosamine transmembrane transporter activity
GO:0006805
P:xenobiotic metabolic process
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References (12)[1] “Molecular characterization of human UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter, a novel nucleotide sugar transporter with dual substrate specificity.” Muraoka M.et.al. 11322953 [2] “Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain.” Nagase T.et.al. 9039502 [3] “Complete sequencing and characterization of 21,243 full-length human cDNAs.” Ota T.et.al. 14702039 [4] “The DNA sequence and biological annotation of human chromosome 1.” Gregory S.G.et.al. 16710414 [5] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [6] “Nucleotide-sugar transporter SLC35D1 is critical to chondroitin sulfate synthesis in cartilage and skeletal development in mouse and human.” Hiraoka S.et.al. 17952091 [7] “Molecular characterization of human UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter, a novel nucleotide sugar transporter with dual substrate specificity.” Muraoka M.et.al. 11322953 [8] “Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain.” Nagase T.et.al. 9039502 [9] “Complete sequencing and characterization of 21,243 full-length human cDNAs.” Ota T.et.al. 14702039 [10] “The DNA sequence and biological annotation of human chromosome 1.” Gregory S.G.et.al. 16710414 [11] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [12] “Nucleotide-sugar transporter SLC35D1 is critical to chondroitin sulfate synthesis in cartilage and skeletal development in mouse and human.” Hiraoka S.et.al. 17952091
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External Searches:
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Analyze:
Predict TMSs (Predict number of transmembrane segments) | ||||
FASTA formatted sequence |
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1: MAEVHRRQHA RVKGEAPAKS STLRDEEELG MASAETLTVF LKLLAAGFYG VSSFLIVVVN 61: KSVLTNYRFP SSLCVGLGQM VATVAVLWVG KALRVVKFPD LDRNVPRKTF PLPLLYFGNQ 121: ITGLFSTKKL NLPMFTVLRR FSILFTMFAE GVLLKKTFSW GIKMTVFAMI IGAFVAASSD 181: LAFDLEGYAF ILINDVLTAA NGAYVKQKLD SKELGKYGLL YYNALFMILP TLAIAYFTGD 241: AQKAVEFEGW ADTLFLLQFT LSCVMGFILM YATVLCTQYN SALTTTIVGC IKNILITYIG 301: MVFGGDYIFT WTNFIGLNIS IAGSLVYSYI TFTEEQLSKQ SEANNKLDIK GKGAV