2.A.7.24.1
The mitochondrial thiamine-repressible putative thiamine pyrophosphate (TPP) transporter, Thi74 (370 aas; 10 TMSs in a 2 + 8 arrangement) (Mojzita and Hohmann, 2006)
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| Accession Number: | Q04083 |
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| Protein Name: | Thi74 |
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| Length: | 370 |
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| Molecular Weight: | 41385.00 |
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| Species: | Saccharomyces cerevisiae (Baker's yeast) [4932] |
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| Number of TMSs: | 10 |
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| Location1 / Topology2 / Orientation3: |
Mitochondrion membrane1 / Multi-pass membrane protein2 |
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| Substrate |
thiamine(1+) diphosphate |
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| DIP: |
DIP-5126N
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| RefSeq: |
NP_010726.1
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| Entrez Gene ID: |
852048
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| Pfam: |
PF00892
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| KEGG: |
sce:YDR438W
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[1] “The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.” Jacq C. et.al. 9169867
[2] “Topology models for 37 Saccharomyces cerevisiae membrane proteins based on C-terminal reporter fusions and predictions.” Kim H. et.al. 12524434
[3] “Pdc2 coordinates expression of the THI regulon in the yeast Saccharomyces cerevisiae.” Mojzita D. et.al. 16850348
[4] “A global topology map of the Saccharomyces cerevisiae membrane proteome.” Kim H. et.al. 16847258
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1: MNRVGIDVDH MIGVLLLAVV VVFWVGASCL TNELLETNAY NKPFFLTYLN ISSFALYLTP
61: DLWRIIQSRR KSLQERTERT LPIHTQESFS EFLPLLSSTP STSSNLSSIA DTKVKDTMRL
121: SLLFCVLWFV ANLAANAALS YTTVASSTIL SSTSSFFTLF LATSLGIETF STKKLLGLFV
181: SLFGIILIVM QSSKQQDSVS ASSFLVGNTL ALLGSLGYSV YTTLLKYEIS SKGLRLDIQM
241: FLGYVGIFTF LLFWPILIIL DITHMETFEL PSNFHISFLV MLNCIIIFVS DYFWCKALIL
301: TSPLVVTVAL TFTIPLAMFA DFVWREAFFT PWYIIGVIFI FVSFFLVNHR GESAVEKDCA
361: AVEKGPILDA