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2.A.7.24.10
SLC family 35 member F2 (SLC35F2; also called DUF914). It regulates cisplatin resistance and promotes malignant progression of pancreatic cancer by regulating RNA binding motif protein 14 (Zhang et al. 2022). SLC35F2 is the receptor of a feline leukemia virus envelope protein required for viral entry into eukaryotic cells (Swapna et al. 2024).

Accession Number:Q8IXU6
Protein Name:Solute carrier family 35 member F2
Length:374
Molecular Weight:41212.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate

Cross database links:

Entrez Gene ID: 54733   
Pfam: PF06027   
KEGG: hsa:54733    hsa:54733    hsa:54733    hsa:54733   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0006810 P:transport

References (24)

[1] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[2] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[3] “The full-ORF clone resource of the German cDNA consortium.”  Bechtel S.et.al.   17974005
[4] “Construction of a transcription map around the gene for ataxia telangiectasia; identification of at least four novel genes.”  Stankovic T.et.al.   9119394
[5] “Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.”  Daub H.et.al.   18691976
[6] “Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.”  Mayya V.et.al.   19690332
[7] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[8] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[9] “The full-ORF clone resource of the German cDNA consortium.”  Bechtel S.et.al.   17974005
[10] “Construction of a transcription map around the gene for ataxia telangiectasia; identification of at least four novel genes.”  Stankovic T.et.al.   9119394
[11] “Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.”  Daub H.et.al.   18691976
[12] “Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.”  Mayya V.et.al.   19690332
[13] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[14] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[15] “The full-ORF clone resource of the German cDNA consortium.”  Bechtel S.et.al.   17974005
[16] “Construction of a transcription map around the gene for ataxia telangiectasia; identification of at least four novel genes.”  Stankovic T.et.al.   9119394
[17] “Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.”  Daub H.et.al.   18691976
[18] “Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.”  Mayya V.et.al.   19690332
[19] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[20] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[21] “The full-ORF clone resource of the German cDNA consortium.”  Bechtel S.et.al.   17974005
[22] “Construction of a transcription map around the gene for ataxia telangiectasia; identification of at least four novel genes.”  Stankovic T.et.al.   9119394
[23] “Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.”  Daub H.et.al.   18691976
[24] “Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.”  Mayya V.et.al.   19690332

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEADSPAGPG APEPLAEGAA AEFSSLLRRI KGKLFTWNIL KTIALGQMLS LCICGTAITS 
61:	QYLAERYKVN TPMLQSFINY CLLFLIYTVM LAFRSGSDNL LVILKRKWWK YILLGLADVE 
121:	ANYVIVRAYQ YTTLTSVQLL DCFGIPVLMA LSWFILHARY RVIHFIAVAV CLLGVGTMVG 
181:	ADILAGREDN SGSDVLIGDI LVLLGASLYA ISNVCEEYIV KKLSRQEFLG MVGLFGTIIS 
241:	GIQLLIVEYK DIASIHWDWK IALLFVAFAL CMFCLYSFMP LVIKVTSATS VNLGILTADL 
301:	YSLFVGLFLF GYKFSGLYIL SFTVIMVGFI LYCSTPTRTA EPAESSVPPV TSIGIDNLGL 
361:	KLEENLQETH SAVL