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Accession Number: | P35206 |
Protein Name: | Mannosyl phosphorylinositol ceramide synthase regulatory protein CSG2 precursor |
Length: | 410 |
Molecular Weight: | 45515.00 |
Species: | Saccharomyces cerevisiae (Baker's yeast) [4932] |
Number of TMSs: | 9 |
Location1 / Topology2 / Orientation3: | Endoplasmic reticulum membrane1 / Multi-pass membrane protein2 |
Substrate | calcium(2+) |
Cross database links:
DIP: | DIP-8095N |
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RefSeq: | NP_009592.1 |
Entrez Gene ID: | 852324 |
KEGG: | sce:YBR036C |
Gene Ontology
GO:0030176
C:integral to endoplasmic reticulum membrane
GO:0030234
F:enzyme regulator activity
GO:0005515
F:protein binding
GO:0006874
P:cellular calcium ion homeostasis
GO:0042493
P:response to drug
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References (7)[1] “A novel protein, CSG2p, is required for Ca2+ regulation in Saccharomyces cerevisiae.” Beeler T.J.et.al. 8125941 [2] “The CLS2 gene encodes a protein with multiple membrane-spanning domains that is important Ca2+ tolerance in yeast.” Takita Y.et.al. 7854312 [3] “Complete DNA sequence of yeast chromosome II.” Feldmann H.et.al. 7813418 [4] “The complete sequence of a 33 kb fragment on the right arm of chromosome II from Saccharomyces cerevisiae reveals 16 open reading frames, including ten new open reading frames, five previously identified genes and a homologue of the SCO1 gene.” Smits P.H.M.et.al. 8091864 [5] “Accumulation of the cytochrome c oxidase subunits I and II in yeast requires a mitochondrial membrane-associated protein, encoded by the nuclear SCO1 gene.” Schulze M.et.al. 2543907 |
External Searches:
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Analyze:
Predict TMSs (Predict number of transmembrane segments) | ||||
FASTA formatted sequence |
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1: MSTTLLWFSS VIGYVIQTKC LSNIQSKKEI SVGPNGTIAT PETNGDNGNS SSLTFYLTFM 61: YFASWLLWVP ASRLWEKMRP MFVSDSDSNR NSQFDNNNSG SVTNEDVDTF SHVLDDPQPR 121: IPAQQQKQKI ISVATFKYVA KLTVLALIMI VADLTYNMAL SLSPAFDVAL MQNTAIFEIV 181: TLLYGVCGIS RKNYVFRNFL IMMNAVIGIL IISYTKATCD MLAGKLSVNP NTGELSDPFL 241: FDRLKGALIC GLGALIMGPF AVLWNRWFCS NISKNENSAV VLVKQSTHMA LIGIIGMVIL 301: LPFIPKFPSR ESVESISLFY NDKSFWFSLL GSIIFGSLPS LISILELNRK APAEYLTTCN 361: LGAIIFMGLA EWVCEPTQTT IVRWEVIGYI MLTVSLLVLS VTLGEGKYHH