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2.A.7.28.5
Solute carrier family 35 member G5, SLC35G5, of 338 aas and 10 TMSs. The gene for SLC35G5 is  commonly mutated in pre-NACT. Patients treated with neoadjuvant chemotherapy (NACT) for advanced high-grade serous ovarian carcinoma have a higher rate and shorter time to platinum-resistant recurrence (Marchocki et al. 2022).

Accession Number:Q96KT7
Protein Name:Solute carrier family 35 member G5
Length:338
Molecular Weight:35161.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:9
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate

Cross database links:

Entrez Gene ID: 83650   
Pfam: PF00892   
KEGG: hsa:83650    hsa:83650    hsa:83650    hsa:83650   

Gene Ontology

GO:0016021 C:integral to membrane

References (12)

[1] “Physical and transcriptional map of the critical region for keratolytic winter erythema (KWE) on chromosome 8p22-p23 between D8S550 and D8S1759.”  Appel S.et.al.   11896452
[2] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[3] “Emergence of primate genes by retrotransposon-mediated sequence transduction.”  Xing J.et.al.   17101974
[4] “Physical and transcriptional map of the critical region for keratolytic winter erythema (KWE) on chromosome 8p22-p23 between D8S550 and D8S1759.”  Appel S.et.al.   11896452
[5] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[6] “Emergence of primate genes by retrotransposon-mediated sequence transduction.”  Xing J.et.al.   17101974
[7] “Physical and transcriptional map of the critical region for keratolytic winter erythema (KWE) on chromosome 8p22-p23 between D8S550 and D8S1759.”  Appel S.et.al.   11896452
[8] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[9] “Emergence of primate genes by retrotransposon-mediated sequence transduction.”  Xing J.et.al.   17101974
[10] “Physical and transcriptional map of the critical region for keratolytic winter erythema (KWE) on chromosome 8p22-p23 between D8S550 and D8S1759.”  Appel S.et.al.   11896452
[11] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[12] “Emergence of primate genes by retrotransposon-mediated sequence transduction.”  Xing J.et.al.   17101974

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MAGSHPYFNL PDSTHPSPPS APPSLRWHQR CQPSGATNGL LVALLGGGLP AGFVGPLSRM 
61:	AYQGSNLPSL ELLICRCLFH LPIALLLKLR GDPLLGPPDI RGWACFCALL NVLSIGCAYS 
121:	AVQVVPAGNA ATVRKGSSTV CSAVLTLCLE SQGLGGYEWC GLLGSILGLI IILGPGLWTL 
181:	QEGTTGVYTT LGYVQAFLGG LALSLGLLVY RSLHFPSCLP TVAFLSGLVG LLGCVPGLFV 
241:	LQTPVLPSDL LSWSCVGAEG ILALVSFTCV GYAVTKAHPA LVCAVLHSEV VVALILQYYM 
301:	LHETVALSDI MGAGVVLGSI AIITARNLSC ERTGKVEE