TCDB » SEARCH

« See all members of the family

2.A.7.3.6 RhtA (YbiF) Threonine/Homoserine Exporter (may export other amino acids including proline, serine, cysteine, histidine and several amino acid analogues, based on resistance phenotypes (Livshits et al., 2003))
Accession Number:	P0AA67
Protein Name:	Uncharacterized inner membrane transporter RhtA aka YbiF aka B0813
Length:	295
Molecular Weight:	31168.00
Species:	Escherichia coli [83333]
Number of TMSs:	10
Location¹ / Topology² / Orientation³:	Cell inner membrane¹ / Multi-pass membrane protein²
Substrate	homoserine, L-threonine

RefSeq:	AP_001444.1 NP_415334.1
Entrez Gene ID:	947045
Pfam:	PF00892
BioCyc:	EcoCyc:EG12134-MONOMER ECOL168927:B0813-MONOMER
KEGG:	ecj:JW0798 eco:b0813
Gene Ontology GO:0016021 C:integral to membrane GO:0005886 C:plasma membrane GO:0006810 P:transport
References (5) [1] “Characterization of the sigma 38-dependent expression of a core Escherichia coli starvation gene, pexB.” Lomovskaya O.L.et.al. 8021175 [2] “A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map.” Oshima T.et.al. 8905232 [3] “The complete genome sequence of Escherichia coli K-12.” Blattner F.R.et.al. 9278503 [4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.” Hayashi K.et.al. 16738553 [5] “Global topology analysis of the Escherichia coli inner membrane proteome.” Daley D.O.et.al. 15919996

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MPGSLRKMPV WLPIVILLVA MASIQGGASL AKSLFPLVGA PGVTALRLAL GTLILIAFFK 
61:	PWRLRFAKEQ RLPLLFYGVS LGGMNYLFYL SIQTVPLGIA VALEFTGPLA VALFSSRRPV 
121:	DFVWVVLAVL GLWFLLPLGQ DVSHVDLTGC ALALGAGACW AIYILSGQRA GAEHGPATVA 
181:	IGSLIAALIF VPIGALQAGE ALWHWSVIPL GLAVAILSTA LPYSLEMIAL TRLPTRTFGT 
241:	LMSMEPALAA VSGMIFLGET LTPIQLLALG AIIAASMGST LTVRKESKIK ELDIN

2.A.7.3.6
RhtA (YbiF) Threonine/Homoserine Exporter (may export other amino acids including proline, serine, cysteine, histidine and several amino acid analogues, based on resistance phenotypes (Livshits et al., 2003))

Cross database links:

Gene Ontology

References (5)

External Searches:

Analyze:

2.A.7.3.6RhtA (YbiF) Threonine/Homoserine Exporter (may export other amino acids including proline, serine, cysteine, histidine and several amino acid analogues, based on resistance phenotypes (Livshits et al., 2003))

Cross database links:

Gene Ontology

References (5)

External Searches:

Analyze:

2.A.7.3.6
RhtA (YbiF) Threonine/Homoserine Exporter (may export other amino acids including proline, serine, cysteine, histidine and several amino acid analogues, based on resistance phenotypes (Livshits et al., 2003))