2.A.7.4.5 UMAMIT14 amino acid efflux transporter of 374 aas and 10 TMSs, a member of the nodulin MtN21 family. It is involved in phloem unloading in Arabidopsis roots (Besnard et al. 2016). UMAMIT14 is expressed in root pericycle and phloem cells and
mediates export of a broad range of amino acids.
Loss-of-function of UMAMIT14 leads to a reduced shoot-to-root and
root-to-medium transfer of amino acids originating from the leaves.
These fluxes were further reduced in an umamti14 umamit18 double
loss-of-function mutant. Thus, UMAMIT14 is involved
in phloem unloading of amino acids in roots, and both UMAMIT14 and
UMAMIT18 are involved in the radial transport of amino acids in roots (Besnard et al. 2016).
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Accession Number: | O80638 |
Protein Name: | WAT1-related protein At2g39510 |
Length: | 374 |
Molecular Weight: | 40674.00 |
Species: | Arabidopsis thaliana (Mouse-ear cress) [3702] |
Number of TMSs: | 10 |
Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
Substrate |
amino acid |
---|
1: MALKTWKPFI TVVSLQFGYA GLSIIAKFAL NQGMSPHVLA SYRHIVATIF IAPFAYFLDR
61: KIRPKMTLSI FFKILLLGLL EPTIDQNLYY TGMKYTSATF TAAMTNVLPA FAFIMAWIFR
121: LEKVNVKKIH SQAKILGTIV TVGGAMLMTV VKGPLIPLPW ANPHDIHQDS SNTGVKQDLT
181: KGASLIAIGC ICWAGFINLQ AITLKSYPVE LSLTAYICFL GSIESTIVAL FIERGNPSAW
241: AIHLDSKLLA AVYGGVICSG IGYYVQGVIM KTRGPVFVTA FNPLSMVIVA ILGSIILAEV
301: MFLGRILGAI VIVLGLYSVL WGKSKDEPSS SFSDMDKELP LSTPQIVLPS KANAKMDTND
361: ASVVISRPNT NESV