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2.A.7.9.16
Solute carrier family 35 member C2, SLC35C2. (Ovarian cancer-overexpressed gene 1 protein) of 365 aas and 10 TMSs. It may play a role in the cellular response to tissue hypoxia, and may be either a GDP-fucose transporter that competes with SLC35C1 for GDP-fucose, or a factor that otherwise enhances the fucosylation of Notch and is required for optimal Notch signaling in mammalian cells (Lu et al. 2010).

Accession Number:Q9NQQ7
Protein Name:Solute carrier family 35 member C2
Length:365
Molecular Weight:40432.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate GDP-fucose

Cross database links:

Entrez Gene ID: 51006   
Pfam: PF03151   
KEGG: hsa:51006   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0006810 P:transport

References (8)

[1] “Assignment of OVCOV1 (alias CGI-15) to human chromosome 20 band q13.1-->q13.2 by fluorescent in situ hybridization.”  Leach R.E.et.al.   11856893
[2] “Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics.”  Lai C.-H.et.al.   10810093
[3] “The DNA sequence and comparative analysis of human chromosome 20.”  Deloukas P.et.al.   11780052
[4] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[5] “Identification, molecular characterization, and tissue expression of OVCOV1.”  Leach R.E.et.al.   12461647
[6] “A quantitative atlas of mitotic phosphorylation.”  Dephoure N.et.al.   18669648
[7] “Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.”  Gauci S.et.al.   19413330
[8] “Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.”  Mayya V.et.al.   19690332

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MGRWALDVAF LWKAVLTLGL VLLYYCFSIG ITFYNKWLTK SFHFPLFMTM LHLAVIFLFS 
61:	ALSRALVQCS SHRARVVLSW ADYLRRVAPT ALATALDVGL SNWSFLYVTV SLYTMTKSSA 
121:	VLFILIFSLI FKLEELRAAL VLVVLLIAGG LFMFTYKSTQ FNVEGFALVL GASFIGGIRW 
181:	TLTQMLLQKA ELGLQNPIDT MFHLQPLMFL GLFPLFAVFE GLHLSTSEKI FRFQDTGLLL 
241:	RVLGSLFLGG ILAFGLGFSE FLLVSRTSSL TLSIAGIFKE VCTLLLAAHL LGDQISLLNW 
301:	LGFALCLSGI SLHVALKALH SRGDGGPKAL KGLGSSPDLE LLLRSSQREE GDNEEEEYFV 
361:	AQGQQ