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2.A.7.9.7
solute carrier family 35, member E2B, SLC35A2B, of 405 aas and 8-10 TMSs. It may take up a nucleobase-containing compounds (Yamada et al. 2017). Mutations in SLC35E2B and the Flrt3 (FLRT3; TC# 8.A.43.1.27) protein can give rise to high myopia, an eye disorder in which both environmental and genetic factors are involved (Swierkowska et al. 2021).

Accession Number:P0CK96
Protein Name:Solute carrier family 35 member E2B
Length:405
Molecular Weight:43777.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:8
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate

Cross database links:

Entrez Gene ID: 728661   
Pfam: PF00892    PF03151   
KEGG: hsa:728661    hsa:728661   

Gene Ontology

GO:0016021 C:integral to membrane

References (10)

[1] “Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.”  Seki N.et.al.   9455484
[2] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[3] “The full-ORF clone resource of the German cDNA consortium.”  Bechtel S.et.al.   17974005
[4] “The DNA sequence and biological annotation of human chromosome 1.”  Gregory S.G.et.al.   16710414
[5] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[6] “Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.”  Seki N.et.al.   9455484
[7] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[8] “The full-ORF clone resource of the German cDNA consortium.”  Bechtel S.et.al.   17974005
[9] “The DNA sequence and biological annotation of human chromosome 1.”  Gregory S.G.et.al.   16710414
[10] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334

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Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence 
1:	MSSSVKTPAL EELVPGSEEK PKGRSPLSWG SLFGHRSEKI VFAKSDGGTD ENVLTVTITE 
61:	TTVIESDLGV WSSRALLYLT LWFFFSFCTL FLNKYILSLL GGEPSMLGAV QMLSTTVIGC 
121:	VKTLVPCCLY QHKARLSYPP NFLMTMLFVG LMRFATVVLG LVSLKNVAVS FAETVKSSAP 
181:	IFTVIMSRMI LGEYTGLLVN LSLIPVMGGL ALCTATEISF NVLGFSAALS TNIMDCLQNV 
241:	FSKKLLSGDK YRFSAPELQF YTSAAAVAML VPARVFFTDV PVIGRSGKSF SYNQDVVLLL 
301:	LTDGVLFHLQ SVTAYALMGK ISPVTFSVAS TVKHALSIWL SVIVFGNKIT SLSAVGTALV 
361:	TVGVLLYNKA RQHQQEALQS LAAATGRAPD DTVEPLLPQD PRQHP