2.A.86.2.1
Purine regulon gene product, YdiK (under PurR control (Ravcheev et al., 2002)) YdiK is of 370 aas with 7 or 8 TMSs. Cryo-EM structures of two pentameric autoinducer-2 exporter from E. coli (TqsA (TC# 2.A.86.1.4) and YdiK (TC# 2.A.86.2.1)) revealed the probable transport mechanism (Khera et al. 2022). Each of the 5 subunits is believed to be a functional unit, and an elevator-type mechanism has been proposed (Khera et al. 2022)..
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| Accession Number: | B1LE48 |
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| Protein Name: | Inner membrane protein YdiK |
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| Length: | 370 |
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| Molecular Weight: | 39865.00 |
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| Species: | Escherichia coli (strain SMS-3-5 / SECEC) [439855] |
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| Number of TMSs: | 10 |
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| Substrate |
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| Entrez Gene ID: |
6144935
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| Pfam: |
PF01594
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| KEGG: |
ecm:EcSMS35_150
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[1] “Insights into the environmental resistance gene pool from the genome sequence of the multidrug-resistant environmental isolate Escherichia coli SMS-3-5.” Fricke W.F. et.al. 18708504
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1: MVNVRQPRDV AQILLSVLFL AIMIVACLWI VQPFILGFAW AGTVVIATWP VLLRLQKFMF
61: GRRSLAVLVM TLLLVMVFII PIALLVNSIV DGSGPLIKAI SSGDMTLPDL AWLNTIPVIG
121: AKLYAGWHNL LDMGGTAIMA KVRPYIGTTT TWFVGQAAHI GRFMVHCALM LLFSALLYWR
181: GEQVAQGIRH FATRLAGVRG DAAVLLAAQA IRAVALGVVV TALVQAVLGG IGLAVSGVPY
241: ATLLTVLMIL SCLVQLGPLP VLIPAIIWLY WTGDTTWGTV LLVWSGVVGT LDNVIRPMLI
301: RMGADLPLIL ILSGVIGGLI AFGMIGLFIG PVLLAVSWRL FAAWVEEVPP PTDQPEEILE
361: ELGEIEKSNK