2.A.87.1.1 The riboflavin uptake transporter, RibU (may also transport roseoflavin and flavin mononucleotide (FMN)) (Burgess et al., 2006). Substrates noted above bind RibU with nM (Vitamin B2 with 0.6 nM) affinity with 1:1 stoichiometry; FAD does not bind (Duurkens et al., 2007).
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Accession Number: | Q1RN04 |
Protein Name: | RibU |
Length: | 206 |
Molecular Weight: | 22972.00 |
Species: | Lactococcus lactis subsp. cremoris (Streptococcus cremoris) [1359] |
Number of TMSs: | 6 |
Location1 / Topology2 / Orientation3: |
Plastid1 / Multi-pass membrane protein2 |
Substrate |
riboflavin |
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[1] “The riboflavin transporter RibU in Lactococcus lactis: molecular characterization of gene expression and the transport mechanism.” Burgess C.M. et.al. 16585736
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1: MSKTRRMVLI AMLAALSTIL LLPILQFPLL PGIDFMKVEL SIIPVLIGVF TLGLGDGFII
61: LFIRSVLWYL LFNQGPSTWI GVPMNFVALG IFMAIVWFFT KKKFSIKNYT VGIVLATIAS
121: VLVMMVLNVF YALPLYRLAA GFDVDKIFAG ATHLFNMGSL SVTLNPTYLL TVVLPFNALQ
181: YIIFALVFGL IVTVFKKNKV VKFYNA