TCDB is operated by the Saier Lab Bioinformatics Group

2.B.111.  The meso-3,5-bis(Trifluoromethyl)Phenyl Picket Calix[4]Pyrrole (TPPCP) Family 

Meso-3,5-bis(trifluoromethyl)phenyl picket calix[4]pyrrole displays excellent fluoride (1) anion transport activity across artificial lipid bilayers showing EC50 = 2.15 μM (at 450 s in EYPC vesicles) with high fluoride over chloride ion selectivity. The high fluoride selectivity of 1 was ascribed to the formation of a sandwich type π-anion-π interaction complex (Patra et al. 2023).

This family belongs to the: Calix[4]Pyrrole Superfamily.

References associated with 2.B.111 family:

Patra, A.K., S. Srimayee, D. Halder, A. Roy, S. Mukherjee, S. Kundu, M. Hossain, R. Saha, C.H. Lee, D. Manna, and I. Saha. (2023). Transmembrane fluoride anion transport by -3,5-bis(trifluoromethyl)phenyl picket calix[4]pyrrole. Chem Commun (Camb) 59: 7407-7410. 37233195