2.B.111. The meso-3,5-bis(Trifluoromethyl)Phenyl Picket CalixPyrrole (TPPCP) Family
Meso-3,5-bis(trifluoromethyl)phenyl picket calixpyrrole displays excellent fluoride (1) anion transport activity across artificial lipid bilayers showing EC50 = 2.15 μM (at 450 s in EYPC vesicles) with high fluoride over chloride ion selectivity. The high fluoride selectivity of 1 was ascribed to the formation of a sandwich type π-anion-π interaction complex (Patra et al. 2023).