2.B.28 The Oligo(aryl-triazole) Anion Transporter (OAT-AT) Family
A series of oligo(aryl-triazole)s (compounds 1-8) have been synthesized, and they served as transmembrane anion transporters by only CH-Cl- interactions. By changing the lipophilicity and anion affinity of the compounds, efficient anion transport with remarkable Cl- vs. HCO3- selectivity has been achieved (Chen et al. 2016). It is not entirely clear if a carrier or channel mechanism is operative.
This family belongs to the: Triazole-containing Channel/Carrier Superfamily.
References associated with 2.B.28 family:
Chen, S., S. Zhang, C. Bao, C. Wang, Q. Lin, and L. Zhu. (2016). Oligo(aryl-triazole)s CHCl- interactions guide chloride efficient and selective transmembrane transport. Chem Commun (Camb) 52: 13132-13135. 27761537