2.B.73.  The Calix[4]Pyrrole Derivative Facilitator (CPDF) Family 

Calix[4]pyrrole derivatives function in the sensing of creatinine and the facilitated transmembrane transport of anions and amino acids (Escobar et al. 2023). Calix[4]pyrrole receptors provide model systems for the quantification of anion-pi interactions and the hydrophobic effect. Calix[4]pyrrole scaffolds have been applied to the development of molecular sensors, ionophores, transmembrane carriers, supramolecular protecting groups and molecular containers modulating chemical reactivity (Escobar et al. 2023).