3.A.1.106.9
SoxR regulon single protein ABC exporter, Sco7008, containing an N-terminal membrane domain and a C-terminal ATPase domain (Shin et al. 2011). SoxR responds to extracellular redox-active compounds. Thus, it is induced in stationary phase during the production
of the benzochromanequinone blue-pigmented antibiotic, actinorhodin (Naseer et al. 2014). Possibly an actinorhodin exporter.
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| Accession Number: | Q9KZE5 |
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| Protein Name: | Putative ABC-transport protein |
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| Length: | 624 |
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| Molecular Weight: | 67273.00 |
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| Species: | Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) [100226] |
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| Number of TMSs: | 6 |
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| Substrate |
actinorhodin |
|---|
1: METTAWTQLY SVMNAKDERR PFARATMRRI GAFARPHRRR IVRFVLLGVA TALLAVATPV
61: LAGKVVDAIV SDGDEGTVVR LALLIALIAV AEAVLGIFSR RLSATLGEGL ILDLRTAVFD
121: HVQRMPVAFF TRTRTGALVS RLNNDVIGAQ RAFSNTLSGV VSNVVTLLLT LAVMLTLSWQ
181: ITLLALVLLP VFVLPARRMG RRMARMQREA AALNAAMGTR MTERFSAPGA TLIKLFGRPE
241: EESAEFADRA RRVADIGVRT ATAQAAFITA LTLVSALALA LVYGLGGFFA LRGTLDAGAV
301: VALALLLTRL YAPLTALAGA RVEVMSALVS FERVFEVLDL APLIDEKPDA RPVPDGPVAV
361: EFDDVRFGYP SADKVSLASL EEVATLDTRG GEEVLHGLSF RAEPGQTIAL VGSSGAGKST
421: IAQLLPRLYD TDGGTVRVGG VDVRELSARS LRDTVGMVTQ DGHLFHDTVR ANLLLARPDA
481: TEDDLWEALR RARLADLVRS LPDGLDTVVG ERGYRLSGGE RQRMTIARLL LARQRVVILD
541: EATAHLDNTS EAAVQEALTE ALQGRTAVVI AHRLSTVRAA DRILVVEAGR IVESGTHEEL
601: LAVDGRYAQL HRTQFERPAL DKAA