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Accession Number: | P18770 |
Protein Name: | CyaB |
Length: | 712 |
Molecular Weight: | 77646.00 |
Species: | Bordetella pertussis [520] |
Number of TMSs: | 6 |
Location1 / Topology2 / Orientation3: | Cell membrane1 / Multi-pass membrane protein2 |
Substrate |
Cross database links:
RefSeq: | NP_879579.1 |
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Entrez Gene ID: | 2664566 |
Pfam: | PF00664 PF00005 PF03412 |
BioCyc: | BPER257313:BP0761-MONOMER |
KEGG: | bpe:BP0761 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005886
C:plasma membrane
GO:0030256
C:type I protein secretion system complex
GO:0005524
F:ATP binding
GO:0042626
F:ATPase activity, coupled to transmembrane m...
GO:0008234
F:cysteine-type peptidase activity
GO:0008565
F:protein transporter activity
GO:0019835
P:cytolysis
GO:0019836
P:hemolysis by symbiont of host erythrocytes
GO:0030253
P:protein secretion by the type I secretion s...
GO:0006508
P:proteolysis
GO:0055085
P:transmembrane transport
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References (2)[1] “Secretion of cyclolysin, the calmodulin-sensitive adenylate cyclase-haemolysin bifunctional protein of Bordetella pertussis.” Glaser P.et.al. 2905265 [2] “Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica.” Parkhill J.et.al. 12910271
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External Searches:
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Analyze:
Predict TMSs (Predict number of transmembrane segments) | ||||
FASTA formatted sequence |
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1: MTSPVAQCAS VPDSGLLCLV MLARYHGLAA DPEQLRHEFA EQAFCSETIQ LAARRVGLKV 61: RRHRPAPARL PRAPLPAIAL DRQGGYFVLA RFEPGADQAV LIQRPGQAPA RLGQAEFEAL 121: WAGELLLCAC AASPTQALAR FDFSWFIPAL VKHRHLIGEV LLISLVLQFI ALLTPLFFQV 181: VMDKVLVNNA METLNVIAVG FLAAILFEAL LTGIRTYLFA HTSSKLDVEL GARLYAHLLR 241: LPLAYFQARR VGDSVARVRE LEHIRAFLTG NAVTVLLDVV FSVVFIAVMF FYSVKLTLVV 301: LAALPCYFLL SLVLTPVLRR RLDVKFNRGA ENQAFLVETV SGIDTVKSLA VEPQWQRNWD 361: RQLAGYVAAG LSVANVAMLA NTGVTLISRL VALGVLWVGA TEVVAQRMTV GELVAFNMLS 421: GHVTQPVIRL AQLWNDFQQT GVSMQRLGDI LNCRTEVAGD KAQLPALRGS IELDRVSFRY 481: RPDAADALRN VSLRIAPGEV VGVVGRSGSG KSTLTRLIQR MFVADRGRVL IDGHDIGIVD 541: SASLRRQLGV VLQESTLFNR SVRDNIALTR PGASMHEVVA AARLAGAHEF ICQLPEGYDT 601: MLGENGVGLS GGQRQRIGIA RALIHRPRVL ILDEATSALD YESEHIIQRN MRDICDGRTV 661: IIIAHRLSAV RCADRIVVME GGEVAECGSH ETLLAAGGLY ARLQALQAGE AG