3.A.1.112.8
Mesenterici Y105 (bacteriocin) ABC exporter and porcessing protease, MesD(E) of 722 aas and 6 TMSs (MesD) (Fremaux et al. 1995). MesDE can transport and catalyze maturation of the two pre-bacteriocins, mesentericin Y105 and B105 (Aucher et al. 2004). Hydrophobic conserved amino acyl residues and the C-terminal GG doublet of the
leader peptide of pre-mesentericin Y105 are critical
for optimal secretion (Aucher et al. 2005). MesE has TC# 8.A.1.4.1.
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| Accession Number: | Q10418 |
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| Protein Name: | Mesentericin-Y105 transport/processing ATP-binding protein MesD |
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| Length: | 722 |
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| Molecular Weight: | 79916.00 |
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| Species: | Leuconostoc mesenteroides [1245] |
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| Number of TMSs: | 6 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
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| Substrate |
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1: MVKTPMFHKK IDYISQVDER DCGVAALAMI LAHYKTRLSL AKLRDLAKTD MEGTTALGIV
61: KAANALDFET MPIQADLSLF DKKDLPYPFI AHVIKEGKYP HYYVVYGMKG DQLLIADPDN
121: TVGKTKMTKA HFNEEWTGVS IFIAPNPTYK PTKEKKRSLT SFIPVITRQK LLVINIVIAA
181: LLVTLVSILG SYYLQGIIDT YIPNNMKNTL GIVSLGLIFA YVIQQLLSYA RDYLLIVMGQ
241: RLSIDIILSY IKHIFELPMS FFATRRTGEI VSRFTDANAI IEALASTMLS VFLDLGILVI
301: VGTVLVVQNS TLFLISLIAI PAYALVVWLF MRPFSKMNND QMQAGSMLSS SIIEDINGVE
361: TIKALNSEAT AYHKIDHEFV TYLEKSFVYA KTEAVQNAIK SLLQLSLNVV ILWVGAQLVM
421: TNKISVGQLI TYNALLGFFT DPLQNIINLQ TKLQQASVAN NRLNEVYLVD SEFKDSHQMT
481: EKITPNSSLV ADHITYKYGF GAPAIDDVSL TITAGEKIAL VGISGSGKST LVKLLVNFFQ
541: PESGTISLGP TPLANLDKHE LRGHINYLPQ EPFIFSGSIM ENLLLGAKPG TTQEDIIRAV
601: EIAEIKDDIE KMSQGFGTEL AESGNISGGQ KQRIALARAI LVDSPVLILD ESTSNLDVLT
661: EKKIIDNLMK LTEKTIIFVA HRLTISQRVD RILTMQSGKI IEDGTHDTLL KAGGFYASLF
721: NH