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| Accession Number: | O43140 |
| Protein Name: | Multidrug resistance protein 1 |
| Length: | 1408 |
| Molecular Weight: | 152145.00 |
| Species: | Cryptococcus neoformans [5207] |
| Number of TMSs: | 12 |
| Substrate | 1H-pyrrole |
Cross database links:
| Pfam: | PF00664 PF00005 |
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Gene Ontology
GO:0016021
C:integral to membrane
GO:0005524
F:ATP binding
GO:0042626
F:ATPase activity, coupled to transmembrane movement of substances
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References (1)[1] “Cloning and characterization of CneMDR1: a Cryptococcus neoformans gene encoding a protein related to multidrug resistance proteins.” Thornewell S.J.et.al. 9409767
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MSASPGLTAA AAGPDHLQAR RDEKVIDSEK DALAHDAHAV NSGIPYPTAT APNVGAPTVP 61: ISVGRVSSAA EGKISRSSIA ASSDTLRNSP LEKPISNAFS KSHPYKKSKF DFLKSRKKKE 121: EEERKNKEKE KEASVLPPVS FFALFRFAAP LEIIAMVLGL VLAVAAGSCQ PLMTLIFGRL 181: TTSFTNYAVI ANQISQGGLT PETSAALQAA KDDLKTQSGH NALYLMAIGI GMFLATWLYM 241: FIWNVTGELN SKRIRERYLA AVLRQEIAYF DDLGAGEVAT RIQTDCHLVQ EGTSEKVALV 301: FQYAGTFVCG FVLAFVRSPR LAGALVSILP VIMLCGGIMM TAMAKYGTAA LDHIAKAGSL 361: AEEVIGSIRT VQAFGKEKIL GDKFADHIEQ SKIVGRKGSI FEGFGLSIMF FVIYAAYALA 421: FFYGGILVSN GQADSGIVIN VFMSILIGSF SMAMLAPELA AVTKARGAAA KLFATIDRVP 481: AIDSASEEGF KPDGLRGEIS FENVKFHYPS RPSIPILKGF TTTFEAGKTF ALVGASGSGK 541: STVVSLIERF YDPVSGVVKL DGRDIRSLNL NWLRQQIGLV SQEPTLFGTT VRGNVEHGLI 601: GSRYENASLE EKFELVKKAC VDANAHNFIM KLPQGYDTMV GERGMLLSGG QKQRVAIARA 661: IVSDPRILLL DEATSALDTQ SEGIVQDALD KASRGRTTIT IAHRLSTIRD ADRIYVMGGG 721: EVLEQGSHND LLANENGPYA QLVNNQKLAQ EAAAEALQVD DDIEDPDDAV FIGGSSPMQE 781: KDKQLHRAVT GRSLASIAMD DIQAKRAEEV AGEDKIPSSF GLYARLLRMN SADKFIYIIA 841: FIAAICAGMV YPSLAILFGK ALSDFEIQDP AELRHALSRS ALWYFITALA AAFVIFFQSA 901: GFSRAGWDLN GVLRKKLFTA TLRHDIEWFD EERNSTGAVT SNLADQPQKV QGLFGPTLGT 961: VVQSCATLIG GCIIGLCYGP LLALIGIACI PILVSGGYIR LKVVVLKDQR MKKLHAASAH 1021: LASEAAGAVK TVASLTREKD VRRIYSEALK APMKLNFRTS IKSQCLFAAS QGLTFCIIAL 1081: VFYIGALWII DAKYSTASFY TVLNSIVFAS IQAGNVFTFV PDASKANSSA ASIFRSIDNE 1141: PAINAESNEG KVLDHKHVVG HVRIEGVHFR YPTRPGVRVL RNLTIDVPAG TYVALVGPSG 1201: CGKSTTIQML ERFYDPLAGR VTLDGIDIKE LNLASYRSQI SLVSQEPTLY AGTIRFNILL 1261: GANKPIEEVT QDEIDAACKD ANIYDFIVSL PDGFDTEVGG KGSQLSGGQK QRIAIARALI 1321: RNPKVLLLDE ATSALDSQSE KVVQEALDKA AKGRTTIAIA HRLSSIQHSD RIYYFSEGRV 1381: AEHGTHQELL AKKGGYYELV QMQNLSRQ